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用于三维(3D)生物打印的支架生物墨水。

Scaffolds Bioink for Three-Dimensional (3D) Bioprinting.

作者信息

An Jin-Hee, Kim Hack-Youn

机构信息

Department of Animal Resources Science, Kongju National University, Yesan 32439, Korea.

Resources Science Research Institute, Yesan 32439, Korea.

出版信息

Food Sci Anim Resour. 2025 Jan;45(1):126-144. doi: 10.5851/kosfa.2024.e120. Epub 2025 Jan 1.

Abstract

Rapid population growth and a corresponding increase in the demand for animal-derived proteins have led to food supply challenges and the need for alternative and sustainable meat production methods. Therefore, this study explored the importance of cell engineering technology-based three-dimensional bioprinting and bioinks, which play key roles in cultured meat production. In cultured meat production, bioinks have a significant effect on cell growth, differentiation, and mechanical stability. Hence, in this study, the characteristics of animal-, plant-, and marine-based bioinks were compared and analyzed, and the impact of each bioink on cultured meat production was evaluated. In particular, animal-based bioinks have the potential to produce cultured meat that is similar to conventional meat and are considered the most suitable bioinks for commercialization. Although plant- and marine-based bioinks are ecofriendly and have fewer religious restrictions, they are limited in terms of mechanical stability and consumer acceptance. Therefore, further research is required to develop and apply optimal animal-based bioinks for commercialization of cultured meat, particularly to improve its mechanical compatibility.

摘要

人口的快速增长以及对动物源蛋白质需求的相应增加,导致了食品供应挑战以及对替代和可持续肉类生产方法的需求。因此,本研究探讨了基于细胞工程技术的三维生物打印和生物墨水的重要性,它们在培养肉生产中发挥着关键作用。在培养肉生产中,生物墨水对细胞生长、分化和机械稳定性有显著影响。因此,在本研究中,对基于动物、植物和海洋的生物墨水的特性进行了比较和分析,并评估了每种生物墨水对培养肉生产的影响。特别是,基于动物的生物墨水有潜力生产出与传统肉类相似的培养肉,被认为是最适合商业化的生物墨水。虽然基于植物和海洋的生物墨水环保且宗教限制较少,但它们在机械稳定性和消费者接受度方面存在局限性。因此,需要进一步研究来开发和应用最佳的基于动物的生物墨水,以实现培养肉的商业化,特别是提高其机械兼容性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ae/11743847/adaacde27e09/kosfa-45-1-126-g1.jpg

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