Plant Antimicrobial Peptides and Their Main Families and Roles: A Review of the Literature.

Antimicrobial peptides (AMPs) are constituent molecules of the innate defense system and are naturally produced by all organisms. AMPs are characterized by a relatively low molecular weight (less than 10 kDa) and a variable number of cysteine residues that form disulfide bonds and contribute to the stabilization of the tertiary structure. In addition, there is a wide repertoire of antimicrobial agents against bacteria, viruses, fungi, and protozoa that can provide a large number of prototype peptides for study and biochemical manipulation. In this sense, plant AMPs stand out because they have a wide range of biological functions against microorganisms and potential applications in medicine and agriculture. Herein, we describe a mini-review of the principal AMP families, such as defensins, lipid transfer proteins (LTPs), thionins, heveins, and cyclotides. The objective of this work was to present the main discoveries regarding the biological activities of these plant AMP families, especially in the last 20 years. We also discuss the current knowledge of their biological activities, gene expression, and possible uses as antimicrobial molecules and in plant biotechnology.