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优化青少年特发性关节炎患者的实验室用药安全监测以推进基于价值的医疗。

Optimizing laboratory medication safety monitoring in patients with juvenile idiopathic arthritis to advance value-based care.

作者信息

Harris Julia G, Holland Michael J, Fox Emily, Favier Leslie, Hoffart Cara, Ibarra Maria, Jones Jordan T, Harris Luke A, Cooper Ashley M

机构信息

Children's Mercy Kansas City, Kansas City, MO, USA.

University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.

出版信息

Clin Rheumatol. 2025 Mar;44(3):1293-1297. doi: 10.1007/s10067-025-07342-x. Epub 2025 Jan 24.

Abstract

INTRODUCTION/OBJECTIVES: Most children with juvenile idiopathic arthritis (JIA) are treated with medications that require safety monitoring labs. Recommended testing includes a creatinine level. However, 87.5% of our visits had a basic metabolic panel (BMP) done. The difference in charges for ordering a serum creatinine versus a BMP is $31, and the difference in matched net revenue per unit is $12.09. Our aim was to increase the ordering of a creatinine rather than a BMP in patients with non-systemic JIA needing methotrexate, leflunomide, and/or biologic medication safety lab monitoring in the Rheumatology Clinic from 12.5 to 80% in 8 months.

METHOD

We utilized quality improvement tools, incorporated this project in our pre-visit planning process, provided physician education, and made updates to our electronic medical record (EMR) order sets. We tracked the percent of patients with JIA taking the pertinent medications who had a creatinine checked rather than a BMP on a run chart to review performance over time.

RESULTS

Our baseline median was 12.5% of visits having a creatinine alone checked instead of a BMP (Fig. 1). We had two shifts in our data with a final center line of 99%. There were no unintended consequences noted during our project.

CONCLUSIONS

Our project optimized medication safety monitoring in patients with JIA by eliminating unnecessary tests to save costs and advance value-based care. Our interventions of education and EMR modifications allowed for standardization of laboratory test ordering. We plan to expand this project to other medications and other diseases to further decrease costs without sacrificing patient safety. Key Points • Most of our patients with JIA that require medication safety monitoring had a basic metabolic panel obtained rather than the recommended serum creatinine. • We significantly increased ordering of a clinically recommended and more cost-effective serum creatinine alone for screening of renal function through quality improvement methodology, physician education, pre-visit planning, and electronic medical record modifications.

摘要

引言/目标:大多数幼年特发性关节炎(JIA)患儿接受的药物治疗需要进行安全性监测实验室检查。推荐的检测项目包括肌酐水平。然而,我们87.5%的就诊病例进行了基本代谢指标(BMP)检查。单独开具血清肌酐检测与BMP检测的费用差异为31美元,每单位匹配净收入差异为12.09美元。我们的目标是在8个月内,将风湿科门诊中需要甲氨蝶呤、来氟米特和/或生物制剂药物安全性实验室监测的非系统性JIA患者中,单独开具肌酐检测而非BMP检测的比例从12.5%提高到80%。

方法

我们运用质量改进工具,将该项目纳入就诊前规划流程,为医生提供教育,并对电子病历(EMR)医嘱集进行更新。我们在趋势图上跟踪接受相关药物治疗的JIA患者中,仅进行肌酐检查而非BMP检查的患者比例,以回顾一段时间内的表现。

结果

我们的基线中位数是,仅12.5%的就诊病例进行了肌酐检查而非BMP检查(图1)。我们的数据出现了两次变化,最终中心线为99%。在我们的项目期间未发现意外后果。

结论

我们的项目通过消除不必要的检查来优化JIA患者的药物安全性监测,以节省成本并推进基于价值的医疗。我们的教育和EMR修改干预措施实现了实验室检查医嘱的标准化。我们计划将该项目扩展到其他药物和其他疾病,以在不牺牲患者安全的情况下进一步降低成本。要点 • 我们大多数需要药物安全性监测的JIA患者进行了基本代谢指标检查,而非推荐的血清肌酐检查。 • 通过质量改进方法、医生教育、就诊前规划和电子病历修改,我们显著提高了单独开具临床推荐且更具成本效益的血清肌酐检测以筛查肾功能的比例。

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