Cretu Andrei, Grosu-Bularda Andreea, Bordeanu-Diaconescu Eliza-Maria, Hodea Florin-Vlad, Ratoiu Vladut-Alin, Dumitru Catalina-Stefania, Andrei Mihaela-Cristina, Neagu Tiberiu-Paul, Lascar Ioan, Hariga Cristian-Sorin
Department 11, Discipline Plastic and Reconstructive Surgery, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Clinic of Plastic Surgery and Reconstructive Microsurgery, Clinical Emergency Hospital of Bucharest, 014461 Bucharest, Romania.
Medicina (Kaunas). 2025 Jan 15;61(1):128. doi: 10.3390/medicina61010128.
Recent advancements in acute burn wound therapy are transforming the management of burn injuries, with a focus on improving healing times, graft integration, and minimizing complications. However, current clinical treatments face significant challenges, including the difficulty of accurately assessing wound depth and tissue viability, which can lead to suboptimal treatment planning. Traditional closure methods often struggle with issues such as delayed wound closure, limited graft survival, inadequate tissue regeneration, and insufficient vascularization. Furthermore, managing infection and minimizing scarring remain persistent obstacles, impacting functional recovery and aesthetic outcomes. Key areas of innovation include advanced imaging techniques that enable more precise assessment of wound depth, size, and tissue viability, allowing for more accurate treatment planning. In addition, new closure strategies are being developed to accelerate wound closure, enhance graft survival, and address challenges such as tissue regeneration, vascularization, and infection prevention. These strategies aim to optimize both functional recovery and aesthetic outcomes, reducing scarring and improving the quality of life for burn patients. While promising, these emerging techniques require further research and clinical validation to refine their effectiveness and expand their accessibility. Together, these innovations represent a significant shift in acute burn care, offering the potential for more personalized, efficient, and effective treatments.
急性烧伤创面治疗的最新进展正在改变烧伤损伤的管理方式,重点是缩短愈合时间、促进移植皮片融合并减少并发症。然而,当前的临床治疗面临重大挑战,包括难以准确评估创面深度和组织活力,这可能导致治疗方案欠佳。传统的闭合方法常常存在诸如创面闭合延迟、移植皮片存活受限、组织再生不足和血管化不充分等问题。此外,控制感染和减少瘢痕形成仍然是持续存在的障碍,影响功能恢复和美观效果。创新的关键领域包括先进的成像技术,这些技术能够更精确地评估创面深度、大小和组织活力,从而实现更准确的治疗规划。此外,正在开发新的闭合策略以加速创面闭合、提高移植皮片存活率,并应对组织再生、血管化和预防感染等挑战。这些策略旨在优化功能恢复和美观效果,减少瘢痕形成并提高烧伤患者的生活质量。尽管前景广阔,但这些新兴技术需要进一步研究和临床验证,以完善其有效性并扩大其可及性。总之,这些创新代表了急性烧伤护理的重大转变,为更个性化、高效和有效的治疗提供了潜力。