Flórez Mauricio Arias, Moreno Gómez Germán Alberto, Flórez Mateo Aguirre, Bueno Isaac López, Gómez Juanita Moreno, Gómez Mateo Moreno, Restrepo Gutiérrez Juan José
Dermatologist - Oncologist, Oncólogos del Occidente, Universidad Tecnológica de Pereira, 660004, Colombia.
Medical Doctor; Clinical Epidemiologist, Public Health PhD, Universidad Tecnológica de Pereira, 660004, Colombia.
Melanoma Manag. 2024 Dec;11(1):2382079. doi: 10.1080/20450885.2024.2382079. Epub 2024 Aug 5.
Melanoma, the deadliest skin cancer, presents significant challenges globally. This study examines survival factors among patients treated at a high-complexity oncology center in Colombia's coffee-growing region. Records from 2010 to 2021 were analyzed, capturing socio-demographics, clinical variables and survival outcomes via Kaplan-Meier and Cox regression. Among 766 patients, factors influencing survival included sex, TNM stage, diagnostic stage, ulceration, metastasis, Breslow thickness ≥1 mm and positive nodes. Age, ulceration, distant stage at diagnosis and Breslow thickness ≥1 mm were associated with mortality. Colombian melanoma patients exhibit lower survival rates compared with global trends. Key survival determinants align with international literature. Enhanced photoprotection and early detection initiatives are imperative.
黑色素瘤是最致命的皮肤癌,在全球范围内构成重大挑战。本研究调查了哥伦比亚咖啡种植区一家高复杂性肿瘤中心治疗的患者的生存因素。分析了2010年至2021年的记录,通过Kaplan-Meier法和Cox回归分析获取社会人口统计学、临床变量和生存结果。在766例患者中,影响生存的因素包括性别、TNM分期、诊断分期、溃疡、转移、Breslow厚度≥1mm和阳性淋巴结。年龄、溃疡、诊断时的远处分期和Breslow厚度≥1mm与死亡率相关。与全球趋势相比,哥伦比亚黑色素瘤患者的生存率较低。关键生存决定因素与国际文献一致。加强光防护和早期检测措施势在必行。