Nelson Cameron, Weigel Isaac, Galet Colette, Wibbenmeyer Lucy, Kurjatko Alexander
Carver College of Medicine, University of Iowa, Iowa City, IA, United States.
Department of Surgery, Division of Acute Care Surgery, University of Iowa, Iowa City, IA, United States.
J Burn Care Res. 2025 Aug 12;46(3):612-619. doi: 10.1093/jbcr/iraf011.
Unplanned extubation rates in burn patients were previously reported at 27% (3 cases per 100 ventilator days). As facial burns pose a unique challenge to tube securement, patients in our unit have surgically placed bite blocks to secure the endotracheal tube at the provider's discretion. Herein, we assessed unplanned extubation rates at our burn center. We performed a retrospective cohort study including burn patients who required mechanical ventilation from 7/01/2015 to 6/30/2023. Demographics, comorbidities, injuries, and hospital course information were collected and compared between patients who had an unplanned extubation and those who did not. Binary logistic regression analyses were performed to identify factors associated with unplanned extubation and ventilator-associated pneumonia (VAP) complication. P < 0.05 was considered significant. Of 360 patients, 17 (4.7%) had unplanned extubations, representing 0.7 cases per 100 ventilator days. There were no significant differences in demographics, comorbidities, or burn injury characteristics between groups. Patients with unplanned extubation were more likely to have an inhalation injury (70.6% vs 42.6%, P = .001), paCO2 ≥ 50 (70.6% vs 39.1%, P = .031), more ventilator days (6 [2-15] vs 2 [1-4] days, P < .001), and more hospital days (14 [8.5-25.5] vs 8 [2-20], P = .020). Ventilator-associated pneumonia rate tended to be higher in the unplanned extubation group (17.6% vs 5.5%, P = .077). On multivariate analysis, inhalation injury was associated with an increased risk of unplanned extubation (odds ratio (OR) = 4.68 [1.59-13.81], P = .005). No patients with bite blocks had an unplanned extubation. Further study on the utility of advanced securement devices is recommended.
先前报道烧伤患者的非计划拔管率为27%(每100个呼吸机日有3例)。由于面部烧伤对管道固定提出了独特挑战,我们科室的患者会根据医生的判断通过手术放置咬块来固定气管插管。在此,我们评估了我们烧伤中心的非计划拔管率。我们进行了一项回顾性队列研究,纳入了2015年7月1日至2023年6月30日期间需要机械通气的烧伤患者。收集了人口统计学、合并症、损伤和住院过程信息,并在发生非计划拔管的患者和未发生非计划拔管的患者之间进行比较。进行二元逻辑回归分析以确定与非计划拔管和呼吸机相关性肺炎(VAP)并发症相关的因素。P<0.05被认为具有统计学意义。在360例患者中,17例(4.7%)发生了非计划拔管,即每100个呼吸机日有0.7例。两组之间在人口统计学、合并症或烧伤损伤特征方面无显著差异。发生非计划拔管的患者更有可能有吸入性损伤(70.6%对42.6%,P=0.001)、动脉血二氧化碳分压(PaCO2)≥50(70.6%对39.1%,P=0.031)、呼吸机使用天数更多(6[2-15]天对2[1-4]天,P<0.001)以及住院天数更多(14[8.5-25.5]天对8[2-20]天,P=0.020)。非计划拔管组的呼吸机相关性肺炎发生率往往更高(17.6%对