TOR通过对植物代谢组的全局调控介导应激反应。

TOR Mediates Stress Responses Through Global Regulation of Metabolome in Plants.

作者信息

Yang Lin, Zhang Ran, Zhang Huan, Yang Yingyu, Fu Liwen

机构信息

Shanghai Collaborative Innovation Center of Agri-Seeds, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China.

Joint Center for Single Cell Biology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China.

出版信息

Int J Mol Sci. 2025 Feb 27;26(5):2095. doi: 10.3390/ijms26052095.

DOI:10.3390/ijms26052095

PMID:40076716

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11900525/

Abstract

The target of rapamycin (TOR) kinase is an evolutionarily conserved atypical Ser/Thr protein kinase present in yeasts, plants, and mammals. In plants, TOR acts as a central signaling hub, playing a pivotal role in the precise orchestration of growth and development. Extensive studies have underscored its significant role in these processes. Recent research has further elucidated TOR's multifaceted roles in plant stress adaptation. Furthermore, mounting evidence indicates TOR's role in mediating the plant metabolome. In this review, we will discuss recent findings on the involvement of TOR signaling in plant adaptation to various abiotic and biotic stresses, with a specific focus on TOR-regulated metabolome reprogramming in response to different stresses.

摘要

雷帕霉素靶蛋白（TOR）激酶是一种在酵母、植物和哺乳动物中存在的进化上保守的非典型丝氨酸/苏氨酸蛋白激酶。在植物中，TOR作为一个核心信号枢纽，在生长和发育的精确协调中发挥着关键作用。大量研究强调了其在这些过程中的重要作用。最近的研究进一步阐明了TOR在植物胁迫适应中的多方面作用。此外，越来越多的证据表明TOR在介导植物代谢组方面的作用。在这篇综述中，我们将讨论TOR信号传导参与植物适应各种非生物和生物胁迫的最新发现，特别关注TOR调节的代谢组重编程以响应不同胁迫。