BenSouf Ikram, Saidani Mariem, Maazoun Asma, Bejaoui Bochra, Larbi Manel Ben, M'Hamdi Naceur, Aggad Hebib, Joly Nicolas, Rojas Janne, Morillo Marielba, Martin Patrick
Animal and Food Resources Laboratory (LRAA), National Agronomic Institute of Tunisia, University of Carthage, 43 Av. Charles Nicolle, Tunis 1082, Tunisia.
Research Unit of Biodiversity and Resource Development in Mountain Areas of Tunisia, UR17AGR14, Higher School of Agriculture of Mateur, University of Carthage, Tunis 1082, Tunisia.
Int J Mol Sci. 2025 Mar 5;26(5):2328. doi: 10.3390/ijms26052328.
Feed additives are crucial in livestock production, enhancing performance, health, and reproductive efficiency. Recently, there has been a shift toward natural biomolecules as feed additives, specifically targeting improved reproductive outcomes and sperm quality. This transition arises from concerns about antibiotic misuse, antimicrobial resistance, and consumer preferences for eco-friendly products, along with the superior bioavailability, lower toxicity, and reduced environmental impact of natural biomolecules compared to synthetic alternatives. Collaboration among researchers, veterinarians, nutritionists, and regulators is essential to ensure safe and effective livestock management. The review explores advancements in using vital biomolecules in reproductive processes, including plant-derived bioactives such as phytochemicals and antioxidants. It investigates not only the mechanisms but also the intricate interactions of these compounds with animals' hormonal and physiological systems. Additionally, the review critically assesses challenges and prospects related to incorporating natural biomolecules into livestock practices. The potential benefits include enhanced reproductive efficiency and improved sperm quality. However, successful implementation requires understanding factors like precise dosing, potential interactions, and long-term health impacts. Overall, this comprehensive review highlights recent research, technological strides, and the future potential of integrating natural biomolecules into animal diets.
饲料添加剂在畜牧生产中至关重要,可提高生产性能、健康水平和繁殖效率。最近,人们倾向于使用天然生物分子作为饲料添加剂,尤其着眼于改善繁殖结果和精子质量。这种转变源于对抗生素滥用、抗菌药物耐药性的担忧,以及消费者对环保产品的偏好,同时天然生物分子与合成替代品相比具有更高的生物利用度、更低的毒性和更小的环境影响。研究人员、兽医、营养学家和监管机构之间的合作对于确保安全有效的畜牧管理至关重要。该综述探讨了重要生物分子在生殖过程中的应用进展,包括植物源生物活性物质,如植物化学物质和抗氧化剂。它不仅研究这些化合物的作用机制,还研究它们与动物激素和生理系统的复杂相互作用。此外,该综述批判性地评估了将天然生物分子纳入畜牧实践的挑战和前景。潜在益处包括提高繁殖效率和改善精子质量。然而,成功实施需要了解精确剂量、潜在相互作用和长期健康影响等因素。总体而言,这篇全面的综述突出了近期的研究、技术进步以及将天然生物分子整合到动物饮食中的未来潜力。