Cao Zhiqiu, Shi Xintao, Sun Li, Fan Zhanhong, Idowu Akinyemi Lydia, Zhang Feng
School of Nursing and Rehabilitation, Nantong University, No.19 Qixiu Road, Nantong City, Jiangsu Province, China.
School of Medicine, Nantong University, Nantong City, Jiangsu Province, China.
Int Arch Occup Environ Health. 2025 Jul;98(4-5):369-384. doi: 10.1007/s00420-025-02137-8. Epub 2025 Mar 27.
Typically affecting people's quality of life, dyssomnia is among the most prevalent chronic illnesses worldwide. A positive correlation between air pollution and dyssomnia has been demonstrated by epidemiological research. However, no meta-analyses evaluating the relationship between the prevalence of dyssomnia in people of all ages and air pollutants (PM, PM, NO, SO, and O) were found.
Conduct a meta-analysis utilizing data from current studies (until 2024) to provide reliable insights into the relationship between air pollution exposure and the likelihood of dyssomnia prevalence.
We systematically searched three databases for studies on air pollution and dyssomnia up to January 15, 2024. Random-effects models were used to estimate the pooled odds ratios (ORs) and 95% confidence intervals (95% CIs). Subgroup analyses, funnel plots, and meta-regression analyses were also performed.
There were 11 studies from 4 different nations that involved 3,328,183 participants in total. The odds ratios (ORs) for PM and PM were 1.29 (1.16-1.44) and 1.13 (1.03-1.23) per 10 µg/m increase in pollutants, respectively. The OR per 10 µg/m increment of gaseous pollutants were 1.06 (1.00-1.12) for NO and 1.16 (1.04-1.31) for O. No significant association was observed between SO and dyssomnia. Adults are more sensitive to air pollution than children or adolescents for that the effects of PM、PM and SO were significantly stronger in adults than children or adolescents. The effect of air pollution on dyssomnia was more significant in developed countries than in developing countries. There was a difference in the subgroup test for PM between developed and developing countries.
This meta-analysis implies the relationship between the air pollution and dyssomnia. Economic status and age may influence the effect. It was suggested to provide guidance for disease prevention and explored potential avenues for further research.
睡眠障碍是全球最常见的慢性病之一,通常会影响人们的生活质量。流行病学研究已证实空气污染与睡眠障碍之间存在正相关。然而,未发现有荟萃分析评估所有年龄段人群的睡眠障碍患病率与空气污染物(PM、PM、NO、SO和O)之间的关系。
利用当前研究(截至2024年)的数据进行荟萃分析,以可靠地洞察空气污染暴露与睡眠障碍患病率之间的关系。
我们系统检索了三个数据库,以查找截至2024年1月15日有关空气污染与睡眠障碍的研究。采用随机效应模型来估计合并比值比(OR)和95%置信区间(95%CI)。还进行了亚组分析、漏斗图分析和荟萃回归分析。
来自4个不同国家的11项研究共涉及3328183名参与者。污染物每增加10μg/m,PM和PM的比值比(OR)分别为1.29(1.16 - 1.44)和1.13(1.03 - 1.23)。气态污染物每增加10μg/m,NO的OR为1.06(1.00 - 1.12),O的OR为1.16(1.04 - 1.31)。未观察到SO与睡眠障碍之间存在显著关联。成年人对空气污染比儿童或青少年更敏感,因为PM、PM和SO对成年人的影响明显强于儿童或青少年。空气污染对睡眠障碍的影响在发达国家比在发展中国家更显著。发达国家和发展中国家在PM的亚组检验上存在差异。
这项荟萃分析揭示了空气污染与睡眠障碍之间的关系。经济状况和年龄可能会影响这种效应。建议为疾病预防提供指导,并探索进一步研究的潜在途径。