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利用食品废弃物底物生产酵母细胞壁多糖-β-葡聚糖和几丁质:生物合成、生产、提取及纯化方法

Production of yeast cell wall polysaccharides-β-glucan and chitin by using food waste substrates: Biosynthesis, production, extraction, and purification methods.

作者信息

Günal-Köroğlu Deniz, Karabulut Gulsah, Mohammadian Fariddudin, Can Karaca Aslı, Capanoglu Esra, Esatbeyoglu Tuba

机构信息

Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Istanbul, Türkiye.

Department of Food Engineering, Faculty of Food Engineering, Sakarya University, Sakarya, Türkiye.

出版信息

Compr Rev Food Sci Food Saf. 2025 May;24(3):e70161. doi: 10.1111/1541-4337.70161.

Abstract

Food waste causes significant environmental and economic challenges worldwide, prompting many nations to prioritize its reduction and recycling. As a nutrient-rich material containing vitamins, proteins, and carbohydrates, it serves as a promising substrate for the cultivation of single-cell microorganisms like yeast. Yeast cell wall polysaccharides (YCWPs), particularly chitin and β-glucans, offer valuable applications in food, pharmaceuticals, and bioprocessing. This review highlights the biosynthesis, production, extraction, and purification of YCWP cultivated on food waste substrates. Key species including Saccharomyces cerevisiae, Pichia pastoris, and Candida spp. are discussed, with a focus on optimizing chitin and β-glucan yield through mechanical, chemical, and enzymatic extraction methods. In addition, the structural and functional properties of β-glucans and chitin in maintaining cell wall stability are explored, emphasizing their potential as prebiotics, dietary fibers, and biodegradable packaging materials. This review also examines the valorization of food waste in yeast cultivation, presenting a sustainable bioprocessing strategy for transforming waste into valuable bioproducts.

摘要

食物浪费在全球范围内造成了重大的环境和经济挑战,促使许多国家将减少食物浪费和回收利用作为优先事项。作为一种富含维生素、蛋白质和碳水化合物的营养物质,食物废料是培养酵母等单细胞微生物的理想底物。酵母细胞壁多糖(YCWPs),特别是几丁质和β-葡聚糖,在食品、制药和生物加工领域具有重要应用价值。本综述重点介绍了以食物废料为底物培养YCWP的生物合成、生产、提取和纯化过程。文中讨论了包括酿酒酵母、巴斯德毕赤酵母和假丝酵母属在内的关键菌种,着重介绍了通过机械、化学和酶法提取方法优化几丁质和β-葡聚糖产量的方法。此外,还探讨了β-葡聚糖和几丁质在维持细胞壁稳定性方面的结构和功能特性,强调了它们作为益生元、膳食纤维和可生物降解包装材料的潜力。本综述还研究了食物废料在酵母培养中的价值转化,提出了一种将废料转化为有价值生物产品的可持续生物加工策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0083/11970350/9920e13d1a5a/CRF3-24-e70161-g003.jpg

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