Rojas-Zambrano Julio G, Rojas-Zambrano Augusto, Rojas-Zambrano Andres F
Gynecology, Dr. Regeneración, Guayaquil, ECU.
General Medicine, Dr. Regeneración, Guayaquil, ECU.
Cureus. 2025 Apr 24;17(4):e82917. doi: 10.7759/cureus.82917. eCollection 2025 Apr.
The development and maintenance of muscular mass, bone density, and general physical strength depend heavily on testosterone, a hormone that plays a complicated and significant role in men's physiology. Beyond these physical advantages, testosterone plays a crucial role in male reproductive health by affecting spermatogenesis (the generation of sperm), libido, and erectile function. It has an effect on many body systems, underscoring its importance for men's physical health and fertility. The goal of this study is to learn more about the critical and varied roles that testosterone plays in healthy men's physiological functioning. The following MeSH terms were used in a PubMed search that covered the years 1998 to the present: (((testosterone) OR (androgens)) OR (testosterone insufficiency)) AND (healthy men)) AND (testosterone replacement). Descriptive, observational, and experimental studies including healthy men-more especially, those assessing the effects of testosterone therapy-were required for inclusion. Testosterone supplements can have a good impact on a number of important aspects of men's health, such as vascular endothelial function, mood (particularly in lowering depression), muscle strength, bone health, and sexual function. Small sample sizes and a dearth of studies, however, limit these findings, highlighting the need for more investigation to completely comprehend the wider impacts of testosterone on men's health. Testosterone therapy has modest advantages, especially for men who have hypogonadism symptoms and low testosterone levels. These advantages include better vascular function, mood, muscle strength, bone density, and sexual health in healthy men. Considering the prospective benefits of testosterone therapy, more investigation and clinical testing are necessary to completely comprehend its effects and improve therapeutic modalities. Further research will better define the function of testosterone in both healthy and deficient men, which will eventually result in more accurate and successful treatment plans.
肌肉质量、骨密度和总体体力的发展与维持在很大程度上依赖于睾酮,这是一种在男性生理过程中发挥复杂且重要作用的激素。除了这些身体方面的优势,睾酮在男性生殖健康中也起着关键作用,它会影响精子发生(精子的生成)、性欲和勃起功能。它对许多身体系统都有影响,凸显了其对男性身体健康和生育能力的重要性。本研究的目的是更深入了解睾酮在健康男性生理功能中所起的关键且多样的作用。在PubMed搜索中使用了以下医学主题词(MeSH),搜索涵盖了1998年至今的文献:(((睾酮) 或 (雄激素)) 或 (睾酮不足)) 且 (健康男性)) 且 (睾酮替代)。纳入的研究要求是包括健康男性的描述性、观察性和实验性研究,尤其是那些评估睾酮治疗效果的研究。睾酮补充剂对男性健康的多个重要方面可能会产生良好影响,如血管内皮功能、情绪(特别是在减轻抑郁方面)、肌肉力量、骨骼健康和性功能。然而,样本量小以及研究匮乏限制了这些发现,这突出表明需要更多研究来全面理解睾酮对男性健康的更广泛影响。睾酮治疗有一定益处,特别是对于有性腺功能减退症状且睾酮水平低的男性。这些益处包括健康男性的血管功能、情绪、肌肉力量、骨密度和性健康得到改善。考虑到睾酮治疗的潜在益处,需要更多研究和临床试验来全面理解其效果并改进治疗方式。进一步的研究将更好地界定睾酮在健康男性和睾酮缺乏男性中的作用,最终将产生更准确、更有效的治疗方案。