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儿童牙科中用于治疗牙齿或口腔感染的抗生素使用:意大利牙医之间的知识与处方实践

Antibiotics Use for Dental or Oral Cavity Infections in Pediatric Dentistry: Knowledge and Prescribing Practices Between Italian Dentists.

作者信息

Barone Martina, Basilicata Michele, Bruno Giovanni, Bacci Christian, Bollero Patrizio, Docimo Raffaella, Gracco Antonio, De Stefani Alberto, Cavallari Filippo

机构信息

Department of Neuroscience, School of Dentistry, University of Padova, 35121 Padua, Italy.

UOSD Special Care Dentistry, Department of Experimental Medicine and Surgery, University of Roma Tor Vergata, 00133 Rome, Italy.

出版信息

Antibiotics (Basel). 2025 Mar 31;14(4):357. doi: 10.3390/antibiotics14040357.

Abstract

UNLABELLED

In pediatric dentistry, antibiotics are currently prescribed for both therapeutic and prophylactic purposes. Antibiotic therapy can be prescribed for the treatment of diffuse dental or oral cavity infections, always as a complement to the most suitable dental procedure for the specific case. The aim of this study was to investigate the knowledge regarding the use and prescribing practices of antibiotics in pediatric patients in a sample of Italian dentists by using an anonymous and telematic questionnaire.

METHODS

A specially prepared questionnaire was electronically transmitted to a cohort of Italian dentists. The questionnaire consisted of two parts: demographic information and general knowledge of antibiotic prescription in pediatric dentistry. The statistical analysis of the obtained data was performed.

RESULTS

The study sample consisted of 242 Italian dentists. Poor statistically significant differences emerged between specialists in Pediatric Dentistry and dentists without specialization or specialists in other branches, as well as between dentists who, in their clinical activity, mainly treat children/adolescents or adults. For the complementary treatment of dental or oral cavity infections, Amoxicillin was the antibiotic indicated as the first choice for pediatric patients with no allergy to penicillins by most of the sample, while more than 20% of dentists would prescribe Clindamycin in patients with an allergy to penicillin. The knowledge regarding the dosage of administration of the chosen antibiotic appeared not to be sufficient.

CONCLUSIONS

An improvement in the knowledge of the Guidelines in Pediatric Dentistry appeared necessary regarding the posology of the antibiotic of choice. More information about the adverse effects of Clindamycin is needed.

摘要

未标注

在儿童牙科中,目前抗生素被用于治疗和预防目的。抗生素治疗可用于治疗弥漫性牙齿或口腔感染,始终作为针对具体病例的最合适牙科治疗程序的补充。本研究的目的是通过使用匿名电子问卷,调查意大利牙医样本中有关儿科患者抗生素使用和处方习惯的知识。

方法

一份专门编制的问卷以电子方式发送给一组意大利牙医。问卷由两部分组成:人口统计学信息和儿童牙科抗生素处方的一般知识。对获得的数据进行了统计分析。

结果

研究样本包括242名意大利牙医。儿童牙科专科医生与非专科牙医或其他科室专科医生之间,以及在临床活动中主要治疗儿童/青少年或成人的牙医之间,在统计学上出现的差异不显著。对于牙齿或口腔感染的辅助治疗,阿莫西林是大多数样本中对青霉素无过敏反应的儿科患者首选的抗生素,而超过20%的牙医会给对青霉素过敏的患者开克林霉素。关于所选抗生素给药剂量的知识似乎不足。

结论

在儿童牙科指南中,关于首选抗生素的剂量学知识似乎有必要改进。需要更多关于克林霉素不良反应的信息。

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