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一期双侧股骨距引导下短柄髋关节置换术中的围手术期患者血液管理

Perioperative patient blood management in one-stage bilateral calcar-guided short stem hip arthroplasty.

作者信息

Noufal Yazan, Brenneis Marco, Dargel Jens, Boettner Friedrich, Schmitz Felix, Rehbein Philipp

机构信息

St. Josefs Hospital, Wiesbaden, Germany.

Hospital for Special Surgery, New York, USA.

出版信息

Arch Orthop Trauma Surg. 2025 May 15;145(1):292. doi: 10.1007/s00402-025-05912-x.

Abstract

BACKGROUND

Total hip arthroplasty is the standard treatment for end stage osteoarthritis of the hip joint. In Germany about 180.000 procedures are performed every year. While most surgeries are performed unilaterally there is an increasing number of single-stage bilateral (SSBL) hip arthroplasties performed. The goal of this study was to demonstrate the safety of SSBL-procedures in terms of blood loss and blood transfusion rates using specific perioperative protocols.

METHODS

Data were collected from 469 patients who underwent one-stage bilateral hip arthroplasty in a single institution, between 2020 and 2023. The current study included patients who were operated on using a minimal-invasive anterolateral approach with a cementless calcar-guided short stem hip prosthesis. The patient's age, sex, comorbidities, medication and preoperative laboratory parameters were gathered as well as the intraoperative blood loss, postoperative hemoglobin levels, blood transfusions and the perioperative administration of tranexamic acid.

RESULTS

Out of 469 patients who underwent SSBL hip arthroplasty, nine (1.9%) required blood transfusions after surgery. In total, 14 red blood cell concentrates (RBC) were transfused (0.029 RBCs per patient). The use of tranexamic acid significantly reduced the need for RBCs (p-value 0.018). Female sex, older age (> 76 years), low body mass index and body weight as well as lower preoperative hemoglobin levels were associated with an increased risk of RBC transfusion.

DISCUSSION

This study demonstrated that SSBL hip arthroplasty, when combined with a minimally invasive approach (anterolateral in supine position), cementless short stem implants, and optimized blood management (including the use of tranexamic acid), is a safe procedure in terms of blood loss and transfusion risk.

摘要

背景

全髋关节置换术是髋关节终末期骨关节炎的标准治疗方法。在德国,每年约进行18万例此类手术。虽然大多数手术是单侧进行的,但单阶段双侧髋关节置换术的数量在不断增加。本研究的目的是通过特定的围手术期方案,在失血和输血率方面证明单阶段双侧髋关节置换术的安全性。

方法

收集了2020年至2023年期间在单一机构接受一期双侧髋关节置换术的469例患者的数据。本研究纳入了采用微创前外侧入路、使用无骨水泥距骨引导短柄髋关节假体进行手术的患者。收集了患者的年龄、性别、合并症、用药情况和术前实验室参数,以及术中失血量、术后血红蛋白水平、输血情况和围手术期氨甲环酸的使用情况。

结果

在469例行单阶段双侧髋关节置换术的患者中,9例(1.9%)术后需要输血。总共输注了14单位红细胞浓缩液(每位患者0.029单位红细胞)。氨甲环酸的使用显著降低了红细胞输注需求(p值0.018)。女性、年龄较大(>76岁)、低体重指数和体重以及术前较低的血红蛋白水平与红细胞输血风险增加相关。

讨论

本研究表明,单阶段双侧髋关节置换术与微创入路(仰卧位前外侧)、无骨水泥短柄植入物以及优化的血液管理(包括使用氨甲环酸)相结合,在失血和输血风险方面是一种安全的手术方法。

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