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一项旨在减轻痴呆症照料者痛苦的电子健康干预措施的成本效益分析:iSupport随机对照试验的结果。

Cost-consequence analysis of an e-health intervention to reduce distress in dementia carers: results from the iSupport randomised controlled trial.

作者信息

Anthony Bethany, Doungsong Kodchawan, MacLeod Catherine, Flynn Greg, Masterson-Algar Patricia, Goulden Nia, Egan Kieren, Jackson Kiara, Kurana Suman, Hughes Gwenllian, Innes Ryan, Connaghan John, Proctor Danielle, Ismail Fatene Abakar, Hoare Zoe, Spector Aimee, Stott Joshua, Windle Gill, Edwards Rhiannon Tudor

机构信息

Centre for Health Economics and Medicines Evaluation (CHEME), Bangor University, Bangor, UK

Centre for Health Economics and Medicines Evaluation (CHEME), Bangor University, Bangor, UK.

出版信息

BMJ Open. 2025 May 16;15(5):e095611. doi: 10.1136/bmjopen-2024-095611.

Abstract

OBJECTIVE

The use of e-health interventions has grown in demand due to their accessibility, low implementation costs and their potential to improve the health and well-being of people across a large geographical area. Despite these potential benefits, little is known about the cost-effectiveness of self-guided e-health interventions. The aim of the study was to compare the cost and consequences of 'iSupport', an e-health intervention to reduce mental health issues in dementia carers.

DESIGN

A cost-consequence analysis (CCA) of a multi-centre, single-blind randomised controlled trial of iSupport. The CCA was conducted from a public sector (National Health Service, social care and local authority) perspective plus a wider societal perspective. Delivery costs of iSupport were collected using a bottom-up micro-costing approach.

SETTING

352 participants were recruited from three centres in England, Wales and Scotland.

PARTICIPANTS

Participants eligible for inclusion were adults over the age of 18 years who self-identified as an unpaid carer with at least 6 months of experience caring for an individual with a diagnosis of dementia. Between 12 November 2021 and 31 March 2023, 2332 carers were invited to take part in the study. 352 participants were randomised: 175 randomised to the iSupport intervention group and 177 to the usual care control group. The mean age of participants in the intervention and control groups was 63 and 62, respectively.

MAIN OUTCOME MEASURES

The CCA presented the disaggregated costs and health-related quality of life measured using the EuroQol five-dimension.

RESULTS

There was no significant difference in generic health-related quality of life measured using the EQ-5D-5L (p=0.67). Both groups reported higher mean costs between baseline and 6 months, but the change in costs was significantly lower in the intervention group. Between baseline and 6 months, the mean change in total resource use costs from the public sector perspective was significantly different between groups (p=0.003, r=-0.161) reporting a mean change per participant of £146 (95% CI: -33 to 342) between the intervention and control groups. From the wider societal perspective, there was no significant difference (p=0.23) in the mean change in total resource use and informal care costs between the two groups from baseline to 6 months.

CONCLUSION

Use of iSupport was associated with reduced health and social care resource use costs for carers compared with care-as-usual. Self-guided e-health interventions for dementia carers may have the potential to reduce health and social care resource use and wider societal costs, but evidence relating to their effectiveness and cost-effectiveness is lacking.

TRIAL REGISTRATION NUMBER

ISRCTN17420703.

摘要

目的

由于电子健康干预措施具有可及性、实施成本低以及有可能改善广大地理区域内人们的健康和福祉,其需求不断增长。尽管有这些潜在益处,但对于自我引导式电子健康干预措施的成本效益却知之甚少。本研究的目的是比较“iSupport”(一种旨在减少痴呆症护理人员心理健康问题的电子健康干预措施)的成本和效果。

设计

对iSupport进行多中心、单盲随机对照试验的成本效果分析(CCA)。CCA从公共部门(国民保健服务体系、社会护理和地方当局)角度以及更广泛的社会角度进行。iSupport的交付成本采用自下而上的微观成本核算方法收集。

设置

从英格兰、威尔士和苏格兰的三个中心招募了352名参与者。

参与者

符合纳入条件的参与者为18岁以上的成年人,他们自我认定为无薪护理人员,且有至少6个月照顾被诊断患有痴呆症患者的经验。在2021年11月12日至2023年3月31日期间,邀请了2332名护理人员参与研究。352名参与者被随机分组:175名被随机分配到iSupport干预组,177名被分配到常规护理对照组。干预组和对照组参与者的平均年龄分别为63岁和62岁。

主要结局指标

CCA呈现了使用欧洲五维健康量表测量的分解成本和与健康相关的生活质量。

结果

使用EQ-5D-5L测量的一般健康相关生活质量无显著差异(p=0.67)。两组在基线和6个月之间报告的平均成本均较高,但干预组的成本变化显著较低。在基线和6个月之间,从公共部门角度来看,两组之间总资源使用成本的平均变化存在显著差异(p=0.003,r=-0.161),干预组和对照组每位参与者的平均变化为146英镑(95%CI:-33至342)。从更广泛的社会角度来看,两组从基线到6个月总资源使用和非正式护理成本的平均变化无显著差异(p=0.23)。

结论

与常规护理相比,使用iSupport可降低护理人员的健康和社会护理资源使用成本。针对痴呆症护理人员的自我引导式电子健康干预措施可能有潜力减少健康和社会护理资源使用以及更广泛的社会成本,但缺乏有关其有效性和成本效益的证据。

试验注册号

ISRCTN17420703。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4981/12086930/59ae847f1c4b/bmjopen-15-5-g001.jpg

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