一次探索一种或多种脑细胞类型的脑回路。

Exploring brain circuits, one cell type-or more- at a time.

作者信息

Tasic Bosiljka, Fishell Gord

机构信息

Allen Institute for Brain Science, Seattle, WA 98109, USA.

Harvard Medical School, Blavatnik Institute, Department of Neurobiology, Boston, MA 02115, USA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

出版信息

Neuron. 2025 May 21;113(10):1469-1473. doi: 10.1016/j.neuron.2025.05.001.

DOI:10.1016/j.neuron.2025.05.001

PMID:40403703

Abstract

This issue of Neuron, with accompanying papers in Cell, Cell Genomics, Cell Reports, and Cell Reports Methods, contains studies describing methods for access to neuronal and non-neuronal cell types within the central nervous system. Combining technologies including genetics, virology, genomic enhancers, and RNA sensing, these tools enable targeting the nervous system in an unprecedented manner.

摘要

本期《神经元》杂志以及同期发表于《细胞》《细胞基因组学》《细胞报告》和《细胞报告方法》上的相关论文，包含了一些研究，这些研究描述了获取中枢神经系统内神经元和非神经元细胞类型的方法。通过结合遗传学、病毒学、基因组增强子和RNA传感等技术，这些工具能够以前所未有的方式靶向神经系统。