Lee Eun, Seo Gitae, Im Chae Hyun, Lee So-Yeon, Lee Yong Ju, Kim Hyo-Bin, Jee Hye Mi, Kim Jihyun, Jeon You Hoon, Suh Dong In, Yang Hyeon-Jong, Lee Kee-Jae, Kim Woo Kyung, Ahn Kangmo
Department of Pediatrics, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.
SCH Biomedical Informatics Research Unit, Soonchunhyang University Seoul Hospital, Seoul, Korea.
Allergy Asthma Immunol Res. 2025 May;17(3):317-329. doi: 10.4168/aair.2025.17.3.317.
We investigated the prevalence of asthma and its risk factors in Korean children in 2022, comparing the prevalence with previous data to identify trends in the prevalence of childhood asthma over time.
This nationwide cross-sectional study enrolled 4,038 children aged 6-7 years and 4,269 children aged 12-13 years from 213 randomly selected elementary schools in 2022. The prevalence of asthma in 2022 was compared with those in 1995, 2000, and 2010, with subgroup comparisons classified by gender. A modified International Study of Asthma and Allergies in Childhood questionnaire assessed asthma prevalence with environmental factors.
The prevalence of ''asthma diagnosis ever' in children aged 6-7 years was 9.1%, 9.4%, and 10.4% in 1995, 2000, and 2010, respectively, which was decreased in 2022 (2.1%, < 0.001). The prevalence of 'current asthma' in children aged 6-7 years showed fluctuations (3.5%, 2.0%, 4.2%, and 0.6% in 1995, 2000, 2010, and 2022, respectively) without showing a significant trend. The prevalence of 'asthma diagnosis ever' and 'current asthma' in children aged 6-7 years was significantly higher in males than in females. The prevalence of 'asthma diagnosis ever' in children aged 12-13 years was 3.1% in 1995, with a significant increasing trend in 2000 (5.8%) and 2010 (7.5%), followed by a decrease in 2022 (3.4%). Male sex, a history of bronchiolitis in early life, allergic rhinitis diagnosis ever, and atopic dermatitis diagnosis ever were associated with 'asthma diagnosis ever' in children aged 6-7 years. For children aged 12-13 years, male sex and history of bronchiolitis in early life were independently associated with 'asthma diagnosis ever.'
Childhood asthma prevalence has decreased, varying by asthma definition. The study's findings provide important information for establishing prevention and management strategies of childhood asthma.
我们调查了2022年韩国儿童哮喘的患病率及其危险因素,将该患病率与先前数据进行比较,以确定儿童哮喘患病率随时间的变化趋势。
这项全国性横断面研究于2022年从213所随机选取的小学招募了4038名6-7岁儿童和4269名12-13岁儿童。将2022年的哮喘患病率与1995年、2000年和2010年的患病率进行比较,并按性别进行亚组比较。一份改良的儿童哮喘和过敏国际研究问卷评估了哮喘患病率及环境因素。
6-7岁儿童中“曾经被诊断为哮喘”的患病率在1995年、2000年和2010年分别为9.1%、9.4%和10.4%,在2022年有所下降(2.1%,P<0.001)。6-7岁儿童中“当前哮喘”的患病率呈现波动(1995年、2000年、2010年和2022年分别为3.5%、2.0%、4.2%和0.6%),未显示出显著趋势。6-7岁儿童中“曾经被诊断为哮喘”和“当前哮喘”的患病率男性显著高于女性。12-13岁儿童中“曾经被诊断为哮喘”的患病率在1995年为3.1%,在2000年(5.8%)和2010年(7.5%)呈显著上升趋势,随后在2022年下降(3.4%)。男性、早年有细支气管炎病史、曾经被诊断为过敏性鼻炎以及曾经被诊断为特应性皮炎与6-7岁儿童“曾经被诊断为哮喘”相关。对于12-13岁儿童,男性和早年有细支气管炎病史与“曾经被诊断为哮喘”独立相关。
儿童哮喘患病率有所下降,因哮喘定义而异。该研究结果为制定儿童哮喘的预防和管理策略提供了重要信息。