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机器人手术在腹主动脉髂动脉瘤和闭塞性疾病中的应用:一项系统评价和单臂荟萃分析。

Robotic surgery in abdominal aortoiliac aneurysm and occlusive disease: a systematic review and single-arm meta-analysis.

作者信息

Santana Ana Carolina Bueno, Delgado Lucas Monteiro, Guedes Lucas Soares de Souza Pinto, Bossi Bruna Maffei, de Melo Leite Pedro Henrique Coelho, Pompeu Bernardo Fontel

机构信息

Department of General Surgery, Heliópolis Hospital, São Paulo, SP, Brazil.

Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

出版信息

J Robot Surg. 2025 May 29;19(1):250. doi: 10.1007/s11701-025-02418-x.

Abstract

Abdominal aortic aneurysms (AAA) and aorto-iliac occlusive disease (AIOD) are traditionally managed via open or endovascular techniques. Robotic surgery emerges as an alternative, offering enhanced visualization, precision, and ergonomics. A systematic review was conducted across PubMed, Embase, and Cochrane to identify observational studies up to September 2024. Continuous outcomes were pooled as mean values with 95% confidence intervals (CIs), and binary outcomes as proportions. Heterogeneity was assessed using the Cochrane Q-test and I statistic. Analyses were performed using R (v4.4.1). Ten studies comprising 595 patients were included. Of these, 402 (67.5%) underwent fully robotic procedures and 193 (32.5%) robotic-assisted surgery. AIOD was the primary indication in 70.5% of cases and AAA in 21.5%. Pooled operative time was 301.2 min (95% CI 238.2-380.9), cross-clamping time 74.3 min (95% CI 56.8-97.2), and anastomotic time 45.5 min (95% CI 29.2-71.1). Mean blood loss was 727.5 mL (95% CI 454.4-1164.7), and hospital stay averaged 7.3 days (95% CI 4.8-11.0). Thirty-day mortality was 3% (95% CI 0%-5%), prosthesis patency at 12 weeks was 92% (95% CI 82%-97%), mesenteric ischemia occurred in 5% (95% CI 2%-11%), and conversion to open surgery in 5% (95% CI 2%-8%). Subgroup analysis revealed higher cross-clamping time and blood loss in AAA compared to AIOD. Robotic aortic surgery demonstrates acceptable short-term outcomes in AAA and AIOD, with low morbidity and promising technical feasibility. Further studies with long-term follow-up are needed to validate its role in aortic surgery.

摘要

腹主动脉瘤(AAA)和主-髂动脉闭塞性疾病(AIOD)传统上通过开放手术或血管内技术进行治疗。机器人手术作为一种替代方法出现,具有增强的可视化、精准度和人体工程学优势。通过检索PubMed、Embase和Cochrane进行了一项系统评价,以识别截至2024年9月的观察性研究。连续变量结果合并为均值及95%置信区间(CI),二分变量结果合并为比例。使用Cochrane Q检验和I统计量评估异质性。使用R(v4.4.1)进行分析。纳入了10项研究,共595例患者。其中,402例(67.5%)接受了完全机器人手术,193例(32.5%)接受了机器人辅助手术。AIOD是70.5%病例的主要适应证,AAA是21.5%病例的主要适应证。汇总的手术时间为301.2分钟(95%CI 238.2 - 380.9),交叉阻断时间为74.3分钟(95%CI 56.8 - 97.2),吻合时间为45.5分钟(95%CI 29.2 - 71.1)。平均失血量为727.5毫升(95%CI 454.4 - 1164.7),平均住院时间为7.3天(95%CI 4.8 - 11.0)。30天死亡率为3%(95%CI 0% - 5%),12周时假体通畅率为92%(95%CI 82% - 97%),肠系膜缺血发生率为5%(95%CI 2% - 11%),转为开放手术的比例为5%(95%CI 2% - 8%)。亚组分析显示,与AIOD相比,AAA的交叉阻断时间和失血量更高。机器人主动脉手术在AAA和AIOD中显示出可接受的短期结果,发病率低且技术可行性良好。需要进一步的长期随访研究来验证其在主动脉手术中的作用。

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