2024年埃塞俄比亚巴赫达尔市公立转诊医院急性卒中患者心房颤动的患病率及相关因素：一项横断面研究
Prevalence and associated factors of atrial fibrillation among acute stroke patients at public referral hospitals in Bahir Dar, Ethiopia, 2024: a cross-sectional study.
作者信息
Molla Elias, Ayele Yihealem Yabebal, Ayenew Tewodros, Mekonen Alemtsehay, Yirdaw Agerye Kassa
机构信息
Department of Internal Medicine, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia.
Department of Reproductive Health, School of Public Health, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia.
出版信息
BMC Cardiovasc Disord. 2025 Jun 2;25(1):424. doi: 10.1186/s12872-025-04839-w.
BACKGROUND
Stroke prevalence and disability-adjusted life years (DALYs) lost are rising in Sub-Saharan Africa, where atrial fibrillation (AF) commonly associated with rheumatic valvular heart disease is prevalent. Despite this, there is a paucity of data regarding the association between atrial fibrillation and acute stroke in this region.
OBJECTIVE
To assess the prevalence of atrial fibrillation and associated factors in acute stroke patients admitted to public referral hospitals from 2020 to 2023, Bahir Dar, Ethiopia.
METHODS
Institution based retrospective cross-sectional study was conducted, using sample size of 326, among acute stroke patients who were admitted to two public hospitals, from January 2020 to December 2023, Bahir Dar, Ethiopia. Pre-developed check list was used to extract data from the medical registry. Data were entered using Epi data manager version 4.6 and analyzed using SPSS version 27. Multivariate logistic regression analysis was used, considering a p-value of < 0.05 as statically significant, with a 95% confidence interval.
RESULTS
The proportion of atrial fibrillation among acute stroke patients was 29.1% (95% CI, 24.3-34.4%). The mean age of the participants was 61.63 years [SD ± 16.24]. Age ≥ 65 years (AOR = 4.37, 95% CI 1.618-11.8), hypertension (AOR = 2, 95% CI 1.12-3.5), heart failure (AOR = 4.95, 95% CI 1.7-14.3) and rheumatic heart disease (AOR = 5.7, 95% CI 1.7-18.8) were significant factors associated with atrial fibrillation in acute stroke patients.
CONCLUSION
This study found a high prevalence of atrial fibrillation among acute stroke patients, with many cases newly diagnosed at presentation. It recommends targeted policies and screening programs to address atrial fibrillation risk factors, particularly in high-risk groups. Further large-scale research is needed to better understand the association between atrial fibrillation and stroke.
背景
在撒哈拉以南非洲地区，中风患病率和因残疾调整生命年（DALYs）损失数正在上升，该地区风湿性心脏瓣膜病常伴发的心房颤动（AF）也很普遍。尽管如此，关于该地区心房颤动与急性中风之间关联的数据却很匮乏。
目的
评估2020年至2023年期间埃塞俄比亚巴赫达尔市公立转诊医院收治的急性中风患者中心房颤动的患病率及相关因素。
方法
采用基于机构的回顾性横断面研究，对2020年1月至2023年12月期间在埃塞俄比亚巴赫达尔市两家公立医院收治的急性中风患者进行研究，样本量为326例。使用预先制定的检查表从医疗登记处提取数据。数据使用Epi数据管理器4.6版本录入，并使用SPSS 27版本进行分析。采用多因素逻辑回归分析，将p值<0.05视为具有统计学意义，置信区间为95%。
结果
急性中风患者中心房颤动的比例为29.1%（95%CI，24.3 - 34.4%）。参与者的平均年龄为61.63岁[标准差±16.24]。年龄≥65岁（调整后比值比[AOR]=4.37，95%CI 1.618 - 11.8）、高血压（AOR = 2，95%CI 1.12 - 3.5）、心力衰竭（AOR = 4.95，95%CI 1.7 - 14.3）和风湿性心脏病（AOR = 5.7，95%CI 1.� - 18.8）是急性中风患者心房颤动的显著相关因素。
结论
本研究发现急性中风患者中心房颤动患病率很高，许多病例在就诊时为新诊断。建议制定针对性政策和筛查计划以应对心房颤动风险因素，特别是在高危人群中。需要进一步开展大规模研究以更好地理解心房颤动与中风之间的关联。
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