Hübel Christopher, Johansson Therese, Mundy Jessica, Lin Yuhao, Petersen Liselotte V, Isomaa Rasmus, Birgegård Andreas
National Centre for Register-based Research, Aarhus University, Aarhus, Denmark; Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK; National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust, London, UK; Clinic for Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, German Red Cross Hospitals Westend, Berlin, Germany.
Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Centre for Women's Mental Health during the Reproductive Lifespan - Womher, Uppsala, Sweden.
Psychiatry Res. 2025 Sep;351:116563. doi: 10.1016/j.psychres.2025.116563. Epub 2025 May 24.
In eating disorders, it is unclear if the experience of a trauma alone is sufficient for the more frequent occurrence of binge eating, self-induced vomiting, self-harm, and suicidality or if these ensue primarily in those individuals who develop posttraumatic stress disorder (PTSD). Distribution appropriate regression analyses in the world's largest clinical eating disorder sample in Sweden (n = 8906) tested for associations between trauma or PTSD and 1) eating disorder type, 2) impulsive eating disorder behaviours, 3) non-suicidal self-injury, and 4) different forms of suicidality. Most variables apart from impulsive disordered-eating behaviours were clinician recorded. In Sweden, 16 % of patients had experienced trauma and 4 % had PTSD. Compared with anorexia nervosa restricting subtype, individuals with the binge-eating/purging subtype or purging disorder were significantly more likely to have comorbid PTSD. Comorbid PTSD at registration to clinical services was significantly cross-sectionally associated with more frequent self-injurious and suicidal symptoms and longitudinally with binge eating frequency, and self-injurious and suicidal symptoms at 12-month follow-up. Our results show no clear support for the experience of trauma alone having similar effects. This underscores the importance of assessing traumatic experiences leading to PTSD in clinical settings as they represent treatment complicating factors.