Prakash Jai, Cho Junghyun, Mishra Yogendra Kumar
Department of Chemistry, National Institute of Technology Hamirpur, Hamirpur 177005 H.P., India.
Department of Mechanical Engineering & Materials Science and Engineering Program, State University of New York (SUNY), Binghamton, NY 13902-6000, USA.
Micro Nano Eng. 2022 Apr;14:100100. doi: 10.1016/j.mne.2021.100100. Epub 2021 Dec 20.
The whole world is struggling with current coronavirus pandemic that shows urgent need to develop novel technologies, medical innovations or innovative materials for controlling SARS-CoV-2 infection. The mode of infection of SARS-CoV-2 is still not well known and seems to spread through surface, air, and water. Therefore, the whole surrounding environment needs to be disinfected with continuous function. For that purpose, materials with excellent antiviral properties, cost effective, environmental friendly and practically applicable should be researched. Titanium dioxide (TiO) under ultraviolet light produces strong oxidative effect and is utilized as photocatalytic disinfectant in biomedical field. TiO based photocatalysts are effective antimicrobial/antiviral agents under ambient conditions with potential to be used even in indoor environment for inactivation of bacteria/viruses. Interestingly, recent studies highlight the effective disinfection of SARS-CoV-2 using TiO photocatalysts. Here, scope of TiO photocatalysts as emerging disinfectant against SARS-CoV-2 infection has been discussed in view of their excellent antibacterial and antiviral activities against various bacteria and viruses (e.g. H1N1, MNV, HSV, NDV, HCoV etc.). The current state of development of TiO based nano-photocatalysts as disinfectant shows their potential to combat with SARS-CoV-2 viral infection and are promising for any other such variants or viruses, bacteria in future studies.
全球都在与当前的新冠疫情作斗争,这表明迫切需要开发新技术、医学创新或创新材料来控制新型冠状病毒(SARS-CoV-2)感染。SARS-CoV-2的感染方式仍不清楚,似乎可通过表面、空气和水传播。因此,整个周围环境需要进行持续有效的消毒。为此,应研究具有优异抗病毒性能、成本效益高、环境友好且实际适用的材料。二氧化钛(TiO)在紫外光下会产生强烈的氧化作用,在生物医学领域用作光催化消毒剂。基于TiO的光催化剂在环境条件下是有效的抗菌/抗病毒剂,甚至有潜力在室内环境中用于灭活细菌/病毒。有趣的是,最近的研究强调了使用TiO光催化剂对SARS-CoV-2进行有效消毒。在此,鉴于TiO光催化剂对各种细菌和病毒(如H1N1、MNV、HSV、NDV、HCoV等)具有优异的抗菌和抗病毒活性,讨论了其作为对抗SARS-CoV-2感染的新兴消毒剂的应用范围。基于TiO的纳米光催化剂作为消毒剂的当前发展状况表明它们有潜力对抗SARS-CoV-2病毒感染,并且在未来的研究中对任何其他此类变体或病毒、细菌都很有前景。