Zhang Shuai, Li Wan-Ci, Liu Jiao, Tang Yu, Niu Dan-Ye
Department of Interventional, The First Affiliated Hospital of Soochow University, Suzhou 215000, Jiangsu Province, China.
Department of Clinical Nutrition, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215000, Jiangsu Province, China.
World J Gastrointest Oncol. 2025 May 15;17(5):102647. doi: 10.4251/wjgo.v17.i5.102647.
Malnutrition exacerbates the deterioration in patients with advanced gastrointestinal tumors.
To analyze the effect of enteral nutritional support based on Nutrition Risk Screening 2002 (NRS2002) risk assessment on nutritional function in patients with gastrointestinal tumors.
One hundred twelve patients from April 2022 to April 2024 were included for observation and were divided into a control group and an observation group by random number method, 56 each. Both groups received treatment for four consecutive weeks. The control group received routine enteral nutrition support, while the observation group received enteral nutrition support based on the NRS2002 risk assessment. Nutritional function, intestinal mucosal barrier function, quality of life, and complication rate were compared between the two groups. Statistical analysis was completed using SPSS26.0 and Excel.
After nutritional intervention, transferrin, albumin, hemoglobin, and diamine oxidase levels in the observation group were higher than those in the control group, while C-reactive protein, tumor necrosis factor α, and quality of life scores were lower, with significant differences ( < 0.05). There was no significant difference in complications between groups ( > 0.05), but the complication rate was lower in the observation group.
Enteral nutritional support based on NRS2002 risk assessment for patients with gastrointestinal tumors positively impacts nutritional status and promotes intestinal mucosal barrier function recovery. Patients' quality of life improved, and the incidence of adverse reactions decreased, indicating clinical promotion and application value.
营养不良会加剧晚期胃肠道肿瘤患者的病情恶化。
分析基于2002年营养风险筛查(NRS2002)风险评估的肠内营养支持对胃肠道肿瘤患者营养功能的影响。
纳入2022年4月至2024年4月的112例患者进行观察,采用随机数字法分为对照组和观察组,每组56例。两组均连续治疗4周。对照组接受常规肠内营养支持,观察组接受基于NRS2002风险评估的肠内营养支持。比较两组的营养功能、肠黏膜屏障功能、生活质量及并发症发生率。使用SPSS26.0和Excel完成统计分析。
营养干预后,观察组的转铁蛋白、白蛋白、血红蛋白和二胺氧化酶水平高于对照组,而C反应蛋白、肿瘤坏死因子α及生活质量评分低于对照组,差异有统计学意义(<0.05)。两组并发症发生率比较,差异无统计学意义(>0.05),但观察组并发症发生率较低。
基于NRS2002风险评估对胃肠道肿瘤患者进行肠内营养支持,对营养状况有积极影响,可促进肠黏膜屏障功能恢复。患者生活质量提高,不良反应发生率降低,具有临床推广应用价值。