衰弱和肌少症老年人400米步行测试与基于传感器的日常身体活动之间的关联
Association between the 400-m walk test and sensor-based daily physical activity in frail and sarcopenic older adults.
作者信息
Rogler Jana, Krumpoch Sebastian, Freiberger Ellen, Lindemann Ulrich, Kob Robert
机构信息
Department of Internal Medicine-Geriatrics, Institute for Biomedicine of Ageing (IBA), Friedrich-Alexander-Universität Erlangen-Nürnberg, Nuremberg, Germany.
Department of Geriatrics, Robert Bosch Hospital, Stuttgart, Germany.
出版信息
Eur Geriatr Med. 2025 Jun 26. doi: 10.1007/s41999-025-01262-4.
PURPOSE
Physical activity (PA) is recommended for frail and sarcopenic older adults as an essential means of preventing negative health outcomes and decline in functional abilities. Our objective was to examine the association between the time and/or stops during the 400-m walk test (400MWT) and average daily steps and walking cadence in a German cohort of frail and sarcopenic community-dwelling older adults.
METHODS
For this sub-study the German cohort of 104 frail and sarcopenic older adults (i.e., SPRINTT) aged 80.8 ± 5.2 years was divided into participants having made none or one stop or more than one stops, referred to as non-stoppers and multi-stoppers. The characteristics and general health state (physical function, disease state, concerns about falling) at first observation (FO) and individual last observation (LO) after at least 11 months (mean 24.5 ± 8.5 months) were examined. Daily PA represented by average daily steps and walking cadence was assessed over three to seven days at FO and LO using the activPAL3 micro. Time and stops made during the 400MWT and their association with daily PA were investigated using regression with bootstrapping.
RESULTS
Out of 104 frail and sarcopenic older adults, 84 non-stoppers (female: n = 54; 64.3%) had a median time in 400MWT of 509 s (Inter Quartile Range (IQR) 324-875), a median number of daily steps of 6537 (IQR 1841-19,488) and a median daily walking cadence of 73 steps/minute (IQR 53.3-88.9). 20 multi-stoppers (female: n = 12; 60%) showed a time of 703 s (IQR 479-898), 5642 steps (IQR 2470-11,458) and a cadence of 70.7 steps/minute (IQR 61.4-83.6). Time was significantly associated with average daily steps and walking cadence at both FO and LO, stops alone were not.
CONCLUSION
Gait speed under laboratory conditions can be used in clinical settings and research to estimate daily PA, represented by average daily steps and cadence, in frail and sarcopenic older adults.
目的
对于体弱和患有肌肉减少症的老年人，建议将体育活动（PA）作为预防负面健康结果和功能能力下降的重要手段。我们的目标是在一个德国体弱和患有肌肉减少症的社区居住老年人队列中，研究400米步行测试（400MWT）中的时间和/或停顿与平均每日步数及步行节奏之间的关联。
方法
在这项子研究中，将104名年龄为80.8±5.2岁的德国体弱和患有肌肉减少症的老年人（即SPRINTT队列）分为未停顿或停顿一次的参与者以及停顿超过一次的参与者，分别称为非停顿者和多次停顿者。检查了首次观察（FO）时以及至少11个月（平均24.5±8.5个月）后的个体末次观察（LO）时的特征和总体健康状况（身体功能、疾病状态、跌倒担忧）。在FO和LO时，使用activPAL3微型设备在三到七天内评估以平均每日步数和步行节奏表示的每日PA。使用自抽样回归研究400MWT期间的时间和停顿及其与每日PA的关联。
结果
在104名体弱和患有肌肉减少症的老年人中，84名非停顿者（女性：n = 54；64.3%）在400MWT中的中位时间为509秒（四分位间距（IQR）324 - 875），平均每日步数中位数为6537步（IQR 1841 - 19488），每日步行节奏中位数为73步/分钟（IQR 53.3 - 88.9）。20名多次停顿者（女性：n = 12；60%）的时间为703秒（IQR 479 - 898），步数为5642步（IQR 2470 - 11458），节奏为70.7步/分钟（IQR 61.4 - 83.6）。在FO和LO时，时间均与平均每日步数和步行节奏显著相关，而仅停顿次数则不然。
结论
在临床环境和研究中，实验室条件下的步态速度可用于估计体弱和患有肌肉减少症的老年人以平均每日步数和节奏表示的每日PA。
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