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评估糖尿病患者对胰高血糖素用于低血糖治疗的认知:沙特阿拉伯利雅得的一项横断面研究。

Assessing the Knowledge of Diabetic Patients About Glucagon Use in Hypoglycemia: A Cross-Sectional Study in Riyadh, Saudi Arabia.

作者信息

Hussien Adel, Alkharasani Alhasan M, Alaboudi Zaid A, Alkhathran Saad A, Abu Suliman Talal, Alanazi Abdulmohsen F, Ezzi Maymunah I, Almajid Ghadir J, Almutleeg Zainab H, Msawa Munira A

机构信息

Medical Biochemistry, Dar Al Uloom University, Riyadh, SAU.

College of Medicine, Dar Al Uloom University, Riyadh, SAU.

出版信息

Cureus. 2025 May 29;17(5):e85017. doi: 10.7759/cureus.85017. eCollection 2025 May.

Abstract

Background and aim Glucagon is a critical intervention for severe hypoglycemia in diabetic patients. However, knowledge about its use remains insufficient among patients. This study aimed to assess the knowledge level related to glucagon in diabetic patients in Riyadh, Saudi Arabia. Methods This cross-sectional survey was conducted among diabetic patients aged 18 years and above in Riyadh, Saudi Arabia. Participants were recruited via social media, diabetes mellitus support groups, and healthcare facilities. The questionnaire collected demographic data, diabetes-related information, and knowledge regarding glucagon use. Results The study included 643 respondents, with a majority from the 24 to 34-year age group. Males constituted 60.3% (n=388) of the participants' population. The majority of participants (70.6%, n=454) had type 2 diabetes mellitus (T2DM), whereas 29.4% (n=189) had type 1 diabetes mellitus (T1DM). The majority of respondents stated that they had experienced hypoglycemia (58.3%, n=375), with 43.2% (n=278) experiencing severe hypoglycemia. A total of 69.2% (n=445) of participants were not aware of glucagon injection. Out of those who were aware, 34.3% (n=68) did not have glucagon injection at home, and 17.7% (n=35) were unaware of how to use it. Knowledge of glucagon was higher among younger individuals, those with higher education, and employed participants (p<0.05). T1DM patients showed significantly greater knowledge of glucagon compared to those with T2DM (p<0.05). Those with diabetes for less than five years were more likely to know about the use of glucagon (p<0.05). Conclusions There is a significant gap in glucagon knowledge and availability among diabetic patients in Riyadh. Therefore, diabetic patients should be educated about glucagon, especially those with a longer duration of diabetes.

摘要

背景与目的 胰高血糖素是糖尿病患者严重低血糖的关键治疗手段。然而,患者对其使用的了解仍然不足。本研究旨在评估沙特阿拉伯利雅得糖尿病患者对胰高血糖素的知识水平。方法 这项横断面调查在沙特阿拉伯利雅得18岁及以上的糖尿病患者中进行。参与者通过社交媒体、糖尿病支持小组和医疗机构招募。问卷收集了人口统计学数据、糖尿病相关信息以及关于胰高血糖素使用的知识。结果 该研究纳入了643名受访者,大多数来自24至34岁年龄组。男性占参与者总数的60.3%(n = 388)。大多数参与者(70.6%,n = 454)患有2型糖尿病(T2DM),而29.4%(n = 189)患有1型糖尿病(T1DM)。大多数受访者表示他们经历过低血糖(58.3%,n = 375),其中43.2%(n = 278)经历过严重低血糖。共有69.2%(n = 445)的参与者不知道胰高血糖素注射。在那些知道的人中,34.3%(n = 68)家里没有胰高血糖素注射剂,17.7%(n = 35)不知道如何使用它。年轻个体、受过高等教育的个体以及就业参与者对胰高血糖素的了解更高(p<0.05)。与T2DM患者相比,T1DM患者对胰高血糖素的了解明显更多(p<0.05)。糖尿病病程少于五年的人更有可能了解胰高血糖素的使用(p<0.05)。结论 利雅得糖尿病患者在胰高血糖素知识和可获得性方面存在显著差距。因此,应该对糖尿病患者进行胰高血糖素教育,尤其是糖尿病病程较长的患者。

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