Shimizu Fumitaka, Muto Satoru, Kitamura Kosuke, Kimura Tomoki, China Toshiyuki, Horie Shigeo
Department of Urology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Department of Urology, Juntendo Nerima Hospital, Tokyo, Japan.
Investig Clin Urol. 2025 Jul;66(4):320-328. doi: 10.4111/icu.20250112.
We developed a totally intracorporeal neobladder (ICNB) reconstruction technique, termed the Juntendo technique, which features a more spherical configuration by advancing from a hybrid neobladder reconstruction approach. In this report, we describe this ICNB procedure and its outcomes from our initial clinical experience.
Between March 2022 and December 2024, 20 male patients underwent neobladder reconstruction (hybrid reconstruction in the first 10 and totally intracorporeal reconstruction in the other 10) following robot-assisted radical cystectomy. The reconstruction technique involved detubularization of a 40 cm ileal segment, formation of a spiral posterior wall plate for vertical traction resistance, and circumferential urethroileal anastomosis without a separate enterotomy. The ureters were anastomosed to a 10 cm afferent limb using the Wallace technique. Subsequently, clinical and perioperative outcomes were collected and compared between the hybrid and ICNB groups.
The estimated blood loss or operative time did not significantly differ between the two groups. In both cohorts, no major perioperative complications occurred, and postoperative renal function remained stable. Both groups also achieved high continence rates. At 3-6 months postoperatively, the ICNB group obtained mean values of 174.9 mL for the neobladder volume, 24.2 mL/s for the maximum flow rate, and 10 mL for the post-void residual volume.
ICNB reconstruction using the Juntendo technique is safe and feasible as the hybrid approach while also yielding favorable early functional outcomes. Studies involving larger patient cohorts and longer follow-up periods is warranted for further validation of this technique.
我们开发了一种完全体内新膀胱(ICNB)重建技术,称为顺天堂技术,该技术通过从混合新膀胱重建方法发展而来,具有更球形的结构。在本报告中,我们描述了这种ICNB手术及其在我们初步临床经验中的结果。
2022年3月至2024年12月期间,20例男性患者在机器人辅助根治性膀胱切除术后接受了新膀胱重建(前10例为混合重建,后10例为完全体内重建)。重建技术包括将一段40cm的回肠去管化,形成用于垂直抗牵引的螺旋状后壁板,以及进行无单独肠切开术的环形尿道回肠吻合。使用华莱士技术将输尿管吻合到一段10cm的输入肠段。随后,收集并比较混合组和ICNB组的临床和围手术期结果。
两组之间的估计失血量或手术时间无显著差异。在两个队列中,均未发生重大围手术期并发症,术后肾功能保持稳定。两组的控尿率也都很高。术后3 - 6个月,ICNB组新膀胱容量的平均值为174.9mL,最大尿流率为24.2mL/s,排尿后残余尿量为10mL。
使用顺天堂技术进行ICNB重建与混合方法一样安全可行,同时也能产生良好的早期功能结果。需要进行涉及更大患者队列和更长随访期的研究,以进一步验证该技术。