使用无活动力的睾丸精子进行体外受精/卵胞浆内单精子注射：结果如何？
The use of immotile testicular sperm for in vitro fertilization/intracytoplasmic sperm injection: what are the outcomes?
作者信息
Panken Evan J, Greenberg Daniel R, Nam Catherine S, Hwang Kathleen, Brannigan Robert E, Halpern Joshua A
机构信息
Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Division of Urology, Department of Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
出版信息
F S Rep. 2025 Mar 18;6(2):108-115. doi: 10.1016/j.xfre.2025.03.005. eCollection 2025 Jun.
Sperm extraction for in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) remains the only option for men with azoospermia to father biologic offspring. Even in cases of successful sperm retrieval, the challenge of selecting optimal sperm for use in IVF/ICSI is an area of research interest. Testicular sperm, unlike epididymal or ejaculated sperm, are often immotile, and there remains debate on the use of immotile testicular sperm in IVF/ICSI and how to best assess sperm viability. Therefore, we aimed to summarize the available literature regarding IVF/ICSI outcomes using immotile testicular sperm.
对于无精子症男性而言，提取精子用于体外受精（IVF）/卵胞浆内单精子注射（ICSI）仍是生育亲生后代的唯一选择。即使在成功获取精子的情况下，为IVF/ICSI选择最佳精子的挑战仍是一个研究热点。与附睾精子或射出精子不同，睾丸精子通常不具有运动能力，对于在IVF/ICSI中使用不活动的睾丸精子以及如何最佳评估精子活力仍存在争议。因此，我们旨在总结关于使用不活动睾丸精子进行IVF/ICSI结果的现有文献。
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