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1992年至2021年中国前臂骨折的发病率、患病率和健康负担以及2036年的预测。

The incidence, prevalence, and health burden of forearm fractures in China from 1992 to 2021 and forecasts for 2036.

作者信息

Zeng Yuan, Hu Minhua, Zhang Zhiming, Chen Jiayi, Luan Feifan, Wu ZhiSen, Zheng Chenxiao

机构信息

Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine, Zhongshan, China.

Guangzhou University of Chinese Medicine, Guangzhou, China.

出版信息

Front Public Health. 2025 Jun 24;13:1566421. doi: 10.3389/fpubh.2025.1566421. eCollection 2025.

Abstract

BACKGROUND

Forearm fractures (Fracture of radius and/or ulna) are common worldwide and constitute a significant public-health burden. There is limited epidemiological data on radius and/or ulna fractures in the Chinese population. Using data from the Global Burden of Disease (GBD) 2021 study, this research reports the epidemiology and disease burden of forearm fractures in China, as well as projected trends for the next 15 years.

METHODS

Data on the incidence, prevalence, and years lived with disability (YLDs) for Fractures of the radius and ulna in mainland China from 1992 to 2021 were obtained from the 2021 GBD database. Joinpoint regression analysis was used to analyze epidemiological trends in incidence, prevalence, and age-standardized rates (ASIR, ASPR, ASYR) over the period from 1992 to 2021. The Bayesian Age-Period-Cohort (BAPC) model was employed to project trends in incidence and YLDs for radius and/or ulna fractures in mainland China from 2022 to 2036.

RESULTS

In 2021, there were 5,790,636 radius and/or ulna fractures in China, with 2,724,178 in males and 3,066,459 in females. The age-standardized incidence rate (ASIR) for radius and/or ulna fractures was 404.52 per 100,000, with 375.83 in males and 430.87 in females. The age-standardized years of disability (ASYR) was 2.55 years per 100,000, with 2.22 years in males and 2.82 years in females. From 1990 to 2021, both the ASIR and ASYR increased, with an average annual percent change (EAPC) of 0.09. The incidence of radius and/or ulna fractures peaked in males at ages 30-34, and in females at ages 50-54 and 65-69. Joinpoint regression analysis revealed a decline in incidence and prevalence from 2001 to 2005, followed by a significant increase from 2011 to 2021. Projected data suggests that the ASIR for radius and/or ulna fractures in males will rise from 369 per 100,000 to 374 per 100,000 from 2022 to 2029. This will be followed by a slight decline from 373 per 100,000 in 2030 to 368 per 100,000 in 2036, while the rate in females is expected to steadily increase from 427 per 100,000 in 2022 to 502 per 100,000 in 2036.

CONCLUSION

In 2021, an estimated 5,790,636 radius and/or ulna fractures occurred in China. Prevalence and disability rates were higher among women than among men. After a decline between 2001 and 2005, the incidence, prevalence, and disability burden of these fractures rose sharply from 2011 to 2021. Projections indicate that incidence in men will fall slightly after 2030, whereas it will continue to rise in women. These findings provide critical evidence for shaping public-health policy, designing fracture-prevention programmes, and allocating healthcare resources in China.

摘要

背景

前臂骨折(桡骨和/或尺骨骨折)在全球范围内都很常见,构成了重大的公共卫生负担。关于中国人群桡骨和/或尺骨骨折的流行病学数据有限。本研究利用《2021年全球疾病负担(GBD)》研究的数据,报告了中国前臂骨折的流行病学和疾病负担,以及未来15年的预测趋势。

方法

从《2021年全球疾病负担》数据库中获取了1992年至2021年中国大陆桡骨和尺骨骨折的发病率、患病率和伤残调整生命年(YLDs)数据。采用Joinpoint回归分析来分析1992年至2021年期间发病率、患病率和年龄标准化率(ASIR、ASPR、ASYR)的流行病学趋势。采用贝叶斯年龄-时期-队列(BAPC)模型预测2022年至2036年中国大陆桡骨和/或尺骨骨折的发病率和YLDs趋势。

结果

2021年,中国发生了5790636例桡骨和/或尺骨骨折,其中男性2724178例,女性3066459例。桡骨和/或尺骨骨折的年龄标准化发病率(ASIR)为每10万人404.52例,男性为375.83例,女性为430.87例。年龄标准化伤残年数(ASYR)为每10万人2.55年,男性为2.22年,女性为2.82年。从1990年到2021年,ASIR和ASYR均有所上升,平均年度百分比变化(EAPC)为0.09。桡骨和/或尺骨骨折的发病率在男性30 - 34岁时达到峰值,在女性50 - 54岁和65 - 69岁时达到峰值。Joinpoint回归分析显示,2001年至2005年发病率和患病率有所下降,随后在2011年至2021年显著上升。预测数据表明,男性桡骨和/或尺骨骨折的ASIR将从2022年的每10万人369例上升到2029年的每10万人374例。随后在2030年从每10万人373例略有下降至2036年的每10万人368例,而女性的发病率预计将从2022年的每10万人427例稳步上升至2036年的每10万人502例。

结论

2021年,中国估计发生了5790636例桡骨和/或尺骨骨折。女性的患病率和伤残率高于男性。在2001年至2005年下降之后,这些骨折的发病率、患病率和伤残负担在2011年至2021年急剧上升。预测表明,2030年后男性发病率将略有下降,而女性发病率将继续上升。这些发现为制定中国的公共卫生政策、设计骨折预防方案和分配医疗资源提供了关键证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed73/12235915/d4d690f9fe6b/fpubh-13-1566421-g001.jpg

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