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Unlocking the therapeutic potential of RNA splicing in lung fibrosis: Insights from the SRSF7-PKM axis.

作者信息

Ding Bi-Sen

机构信息

Key Lab of Birth Defects and Related Diseases of Women and Children of MOE, State Key Lab of Biotherapy, State Key Laboratory of Respiratory Health and Multimorbidity, West China Second University Hospital, College of Life Sciences, Sichuan University, Chengdu 610064, China.

出版信息

Acta Pharm Sin B. 2025 Jun;15(6):3351-3352. doi: 10.1016/j.apsb.2025.05.028. Epub 2025 Jun 24.

Abstract
摘要

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本文引用的文献

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RUNX2 promotes fibrosis via an alveolar-to-pathological fibroblast transition.
Nature. 2025 Apr;640(8057):221-230. doi: 10.1038/s41586-024-08542-2. Epub 2025 Feb 5.
2
An injury-induced mesenchymal-epithelial cell niche coordinates regenerative responses in the lung.
Science. 2024 Dec 13;386(6727):eado5561. doi: 10.1126/science.ado5561.
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Lomitapide for the treatment of homozygous familial hypercholesterolaemia in children.
Lancet Diabetes Endocrinol. 2024 Dec;12(12):866-867. doi: 10.1016/S2213-8587(24)00277-8. Epub 2024 Oct 16.
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Sci Transl Med. 2024 Aug 28;16(762):eado5266. doi: 10.1126/scitranslmed.ado5266.
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Tracing the origin of alveolar stem cells in lung repair and regeneration.
Cell. 2024 May 9;187(10):2428-2445.e20. doi: 10.1016/j.cell.2024.03.010. Epub 2024 Apr 4.
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Lung regeneration: diverse cell types and the therapeutic potential.
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The physiology of alternative splicing.
Nat Rev Mol Cell Biol. 2023 Apr;24(4):242-254. doi: 10.1038/s41580-022-00545-z. Epub 2022 Oct 13.
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Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis.
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