代谢与减重手术对特发性颅内高压患者的影响；一项系统评价与荟萃分析。
The Effect of Metabolic and Bariatric Surgery on Patients with Idiopathic Intracranial Hypertension; A Systematic Review and Meta-analysis.
作者信息
Radboy Mahsa, Esparham Ali, Shari'at Moghani Mahta, Einafshar Negar, Ghamari Mohammad Javad, Zandbaf Tooraj
机构信息
Innovative Medical Research Center, MMS.C., Islamic Azad University, Mashhad, Islamic Republic of Iran.
Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Islamic Republic of Iran.
出版信息
Obes Surg. 2025 Jul 17. doi: 10.1007/s11695-025-08068-0.
The current study aimed to evaluate the impact of Metabolic and Bariatric surgery (MBS) on patients with idiopathic intracranial hypertension (IIH) and obesity. A systematic search was performed in the PubMed, Embase, Scopus, and Web of Science databases. A total of 15 studies with 887 patients were included. Our results showed that MBS was associated with intracranial pressure (ICP) reduction with a mean difference of -15.79 mm/Hg (95% CI: -21.38, -10.31, I2 = 85.79%, P < 0.001). Furthermore, MBS was associated with significant resolution of headache, papilledema, and visual disturbances in patients with obesity and IIH. These findings indicate that MBS could improve IIH and decrease symptoms. These findings highlight the significant impact of weight loss achieved through MBS on patients with IIH.
本研究旨在评估代谢与减重手术（MBS）对特发性颅内高压（IIH）合并肥胖患者的影响。我们在PubMed、Embase、Scopus和科学网数据库中进行了系统检索。共纳入15项研究，涉及887例患者。我们的结果显示，MBS与颅内压（ICP）降低相关，平均差值为-15.79 mmHg（95%可信区间：-21.38，-10.31，I2 = 85.79%，P < 0.001）。此外，MBS与肥胖合并IIH患者头痛、视乳头水肿和视觉障碍的显著缓解相关。这些发现表明，MBS可以改善IIH并减轻症状。这些发现突出了通过MBS实现的体重减轻对IIH患者的重大影响。
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