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2型糖尿病中基于人工智能的治疗策略进展:重要更新

Advancement of artificial intelligence based treatment strategy in type 2 diabetes: A critical update.

作者信息

Sen Aniruddha, Mohanraj Palani Selvam, Laxmi Vijaya, Ashique Sumel, Vasudevan Rajalakshimi, Aldahish Afaf, Velu Anupriya, Das Arani, Ehsan Iman, Islam Anas, Yasmin Sabina, Ansari Mohammad Yousuf

机构信息

Department of Biochemistry, All India Institute of Medical Sciences, Gorakhpur, 273008, India.

Department of Pharmacology, All India Institute of Medical Sciences, Gorakhpur, 273008, India.

出版信息

J Pharm Anal. 2025 Jun;15(6):101305. doi: 10.1016/j.jpha.2025.101305. Epub 2025 Apr 10.

Abstract

In the unrelenting race to strive to dominate type 2 diabetes mellitus (T2DM) care better, this review paper sets out on a significant discovery trip across recent advancements in treatment and the blooming era of artificial intelligence (AI) utilities. Given the considerable global burden of T2DM, innovative therapeutic approaches to improve patient outcomes remain a public health priority. This review first provides an in-depth analysis of the current state of therapy, from novel pharmacotherapy to lifestyle interventions and new treatment methods. At the same time, the rapidly increasing role of AI in diabetes care is woven into the story, mainly targeting how insulin therapy can be modified and personalized through algorithms and predictive modelling. It leaves a deep review of their pre-existing synergies, which helps understand how collaborative opportunities will unlock the future of T2DM care. This critical role is shown by integrating recent therapeutic advances and AI with overall showcasing better screening, diagnosis, and therapeutics decision-making to outcome prediction in T2DM. The review emphasizes how AI applications in insulin therapy have transformative potential in diabetes care. These person-centred approaches to T2DM management, which are more effective and personalized than some traditional strategies, only work because of the often-hidden synergies between AI algorithms in areas such as diagnostic criteria, predictive methods, and familiar classification tools for subgroups with relevant aspects/predictors on prognosis or treatment responsiveness.

摘要

在这场力求更好地主导2型糖尿病(T2DM)护理的不懈竞赛中,本综述文章踏上了一段意义重大的探索之旅,涵盖治疗方面的最新进展以及人工智能(AI)应用蓬勃发展的时代。鉴于T2DM在全球造成的巨大负担,创新治疗方法以改善患者预后仍是公共卫生的优先事项。本综述首先深入分析了当前的治疗现状,从新型药物治疗到生活方式干预以及新的治疗方法。与此同时,AI在糖尿病护理中迅速增长的作用也贯穿其中,主要聚焦于如何通过算法和预测模型对胰岛素治疗进行调整和个性化。文章深入探讨了它们已有的协同作用,这有助于理解合作机会将如何开启T2DM护理的未来。通过将近期治疗进展和AI与整体情况相结合,展示从更好的筛查、诊断、治疗决策到T2DM预后预测的关键作用。该综述强调了AI在胰岛素治疗中的应用在糖尿病护理方面具有变革潜力。这些以患者为中心的T2DM管理方法比一些传统策略更有效且更具个性化,之所以能够发挥作用,是因为在诊断标准、预测方法以及针对具有相关预后或治疗反应方面/预测因素的亚组的常见分类工具等领域,AI算法之间往往存在隐藏的协同作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b7c/12268056/119863955891/ga1.jpg

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