姜黄素作为一种天然治疗剂：潜在临床用途及作用机制的快速综述
Curcumin as a Natural Therapeutic Agent: A Rapid Review of Potential Clinical Uses and Mechanisms of Action.
作者信息
Mohajeri Mohammad, Momenai Reza, Karami-Mohajeri Somayyeh, Ohadi Mandana, Raeisi Estabragh Mohammad Amin
机构信息
Department of Pharmacology and Toxicology, School of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran.
Nimeh Shaaban Hospital, Kerman, Iran.
出版信息
Iran J Pharm Res. 2025 Feb 4;24(1):e156983. doi: 10.5812/ijpr-156983. eCollection 2025 Jan-Dec.
CONTEXT
Curcumin, a natural compound derived from the rhizome of the turmeric plant, exhibits various pharmacological and therapeutic effects through distinct cellular and molecular mechanisms.
EVIDENCE ACQUISITION
Given the therapeutic applications and pharmacological properties of curcumin, it is essential to explore its pharmacological effects for potential use in clinical research. Notably, curcumin demonstrates significant antioxidant, anti-inflammatory, and anti-cancer properties. Importantly, no side effects or specific toxicity have been reported for curcumin.
RESULTS
Curcumin, as a natural compound, can be utilized as a drug supplement in treatment regimens for various diseases. Numerous clinical studies have indicated that curcumin enhances the efficacy of chemotherapy drugs or mitigates their side effects when used concurrently.
CONCLUSIONS
This review presents an overview of studies conducted on the pharmacological effects and therapeutic properties of curcumin.
背景
姜黄素是一种从姜黄植物根茎中提取的天然化合物，通过独特的细胞和分子机制展现出多种药理和治疗作用。
证据获取
鉴于姜黄素的治疗应用和药理特性，探索其药理作用以用于临床研究的潜在用途至关重要。值得注意的是，姜黄素具有显著的抗氧化、抗炎和抗癌特性。重要的是，尚未有关于姜黄素副作用或特定毒性的报道。
结果
姜黄素作为一种天然化合物，可作为药物补充剂用于各种疾病的治疗方案。众多临床研究表明，姜黄素在同时使用时可提高化疗药物的疗效或减轻其副作用。
结论
本综述概述了关于姜黄素药理作用和治疗特性的研究。
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