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用于炎症性肠病的补充药物和人参——基于科学,但会有成效吗?

Complementary medicines and ginseng for inflammatory bowel disease-rooted in science, but will it bear fruit?

作者信息

Schildkraut Tamar, Srinivasan Ashish R, Nguyen Andrew, Lai Mark, Vasudevan Abhinav

机构信息

Department of Gastroenterology and Hepatology, Eastern Health, Melbourne 3128, Victoria, Australia.

Department of Medicine, University of Melbourne, Melbourne 3084, Victoria, Australia.

出版信息

World J Gastroenterol. 2025 Jul 21;31(27):108524. doi: 10.3748/wjg.v31.i27.108524.

Abstract

This editorial is based on the network pharmacology and study by Qin , which investigated the potential therapeutic mechanisms of () in ulcerative colitis. The key findings from the study included the identification of the targets of and ulcerative colitis, elucidation of mechanistic pathways, and validation of the pharmacological activity and therapeutic effect of panaxadiol, a key active component of . This editorial provides additional context regarding the evidence supporting the use of ginseng and other commonly used complementary therapies that clinicians may encounter. We also aim to highlight potential similarities between the mechanisms of popular complementary and conventional medical therapies.

摘要

这篇社论基于网络药理学以及秦的研究,该研究调查了()在溃疡性结肠炎中的潜在治疗机制。该研究的主要发现包括确定()和溃疡性结肠炎的靶点、阐明作用机制途径,以及验证()的关键活性成分人参二醇的药理活性和治疗效果。这篇社论提供了更多背景信息,以支持人参及临床医生可能遇到的其他常用补充疗法的使用证据。我们还旨在强调常用补充疗法与传统医学疗法在机制上的潜在相似性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ba2/12305131/3b22c01e29a3/wjg-31-27-108524-g001.jpg

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