The Effectivity MultiModality Treatment on Rehabilitation Management of Diabetic Foot Disease Patients for Improvement of Clinical Efficacy & Hemorheological Status.

OBJECTIVE

To evaluate the effectiveness of a multimodal intervention-comprising rehabilitation management and foot preventive measures-on clinical outcomes, hemorheological parameters, and vascular endothelial function in patients with diabetic foot (DF).

METHODS

This retrospective study included 126 patients admitted to our hospital from February 2023 to April 2024. Patients were divided into a control group (n = 63, receiving routine nursing care) and an intervention group (n = 63, receiving routine care plus rehabilitation management combined with foot preventive measures). Key outcome measures included: (1) clinical efficacy; (2) hemorheological indicators-whole blood low-shear viscosity (WBLSV), high-shear viscosity (WBHSV), fibrinogen (FIB), and erythrocyte deformability index (EDI); (3) vascular endothelial function indicators-endothelin (ET), basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF), and calcitonin gene-related peptide (CGRP); (4) self-management ability-Adult Health Self-Management Scale (AHSMSRS), General Self-Efficacy Scale (GSES); and (5) nursing satisfaction-Newcastle Nursing Service Satisfaction Scale (NSNS).

RESULTS

The intervention group had a significantly higher total treatment efficacy rate (92.06% vs 77.78%, P < 0.05). Post-intervention hemorheological parameters (WBLSV, WBHSV, FIB, EDI) and endothelial markers (ET, bFGF, VEGF, CGRP) showed greater improvement in the intervention group (P < 0.05). Similarly, AHSMSRS scores declined and GSES scores improved more markedly in the intervention group (P < 0.05). Nursing satisfaction was also higher (96.83% vs 71.43%, P < 0.05).

CONCLUSION

Compared with routine nursing care alone, the multimodal intervention strategy may improve clinical efficacy, hemorheology, endothelial function, self-management capabilities, and patient satisfaction in diabetic foot care. However, these findings should be interpreted with caution given the retrospective design.