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输尿管结石嵌顿程度能否更好地预测手术成功率和并发症?一种新的分类系统。

Can the degree of ureteral stone impaction better predict surgical success and complications? a new classification system.

作者信息

Şam Emre, Yağmur Mustafa, Akkuş Muhammed Çağrı, Öztürk Koçakgöl Deniz, Emir Büşra, Altay Mehmet Sefa, Akkaş Fatih, Güner Ekrem

机构信息

Department of Urology, University of Health Sciences, Erzurum City Hospital, Erzurum, Turkey.

Department of Radiology, University of Health Sciences, Erzurum City Hospital, Erzurum, Turkey.

出版信息

BMC Urol. 2025 Aug 21;25(1):212. doi: 10.1186/s12894-025-01912-6.

Abstract

BACKGROUND

According to our hypothesis, a classification system that grades stone impaction may better predict surgical success and complications. Therefore, we developed a new classification system, and in this study, we aimed to evaluate the effect of stone impaction and its degree on success and complications of ureteroscopic lithotripsy (URS-L), as well as to investigate preoperative factors predicting stone impaction and its degree.

METHODS

Data of patients over the age of 18 years who underwent URS-L for a single ureteral stone were prospectively collected. First, stone impaction was determined by the primary surgeon using a Likert scale. Subsequently, non-impacted and impacted stones were further divided into two subgroups and classified according to the degree of stone impaction between Grades 1 and 4. Patient characteristics, preoperative non-contrast computed tomography (CT) findings, laboratory values, and intraoperative and postoperative outcomes were analyzed. Stone-free status was defined as the absence of residual stones > 2 mm on non-contrast CT at postoperative month 1.

RESULTS

The study included a total of 211 patients. Operative time, ureteral injury, degree of ureteral injury, failure (nephrostomy placement), hospital stay, and stone-free rates differed significantly between impacted and non-impacted stones. When evaluated by degree of impaction, significant differences were identified in operative time, presence of pyuria, ureteral injury, degree of ureteral injury, failure, hospital stay, and stone-free status. Colic severity, time from pain onset to surgery, location (upper ureter), stone volume, peri-calculus ureteral wall thickness (PUWT), and presence of severe hydronephrosis were found to be predictive factors of stone impaction, while female gender, stone location (upper ureter), and PUWT were independent predictors of Grade 4 stones.

CONCLUSIONS

This study showed that stone impaction and the new classification system are associated with surgical outcomes. Not all non-impacted or impacted stones are the same, and grading according to the interaction of the stone with the ureteral wall can better predict surgical outcomes.

摘要

背景

根据我们的假设,一种对结石嵌顿进行分级的分类系统可能能更好地预测手术成功率和并发症。因此,我们开发了一种新的分类系统,在本研究中,我们旨在评估结石嵌顿及其程度对输尿管镜碎石术(URS-L)成功率和并发症的影响,并研究预测结石嵌顿及其程度的术前因素。

方法

前瞻性收集18岁以上因单一输尿管结石接受URS-L治疗的患者的数据。首先,主刀医生使用李克特量表确定结石嵌顿情况。随后,未嵌顿和嵌顿结石进一步分为两个亚组,并根据结石嵌顿程度在1至4级之间进行分类。分析患者特征、术前非增强计算机断层扫描(CT)结果、实验室值以及术中及术后结果。结石清除状态定义为术后1个月非增强CT上无残留结石>2mm。

结果

该研究共纳入211例患者。手术时间、输尿管损伤、输尿管损伤程度、失败(放置肾造瘘管)、住院时间和结石清除率在嵌顿结石和未嵌顿结石之间存在显著差异。按嵌顿程度评估时,手术时间、脓尿的存在、输尿管损伤、输尿管损伤程度、失败、住院时间和结石清除状态存在显著差异。绞痛严重程度、疼痛发作至手术的时间、位置(上段输尿管)、结石体积、结石周围输尿管壁厚度(PUWT)和严重肾积水的存在被发现是结石嵌顿的预测因素,而女性性别、结石位置(上段输尿管)和PUWT是4级结石的独立预测因素。

结论

本研究表明结石嵌顿和新的分类系统与手术结果相关。并非所有未嵌顿或嵌顿结石都是相同的,根据结石与输尿管壁的相互作用进行分级可以更好地预测手术结果。

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