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酵母及其培养物在反刍动物肠道抗氧化防御调节中的作用机制与应用

Mechanism and application of yeast and its culture in regulating intestinal antioxidant defense in ruminants.

作者信息

Yang Lan, Wu Xiaoxuan, Liu Dacheng

机构信息

College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China.

出版信息

Front Vet Sci. 2025 Aug 7;12:1657244. doi: 10.3389/fvets.2025.1657244. eCollection 2025.

Abstract

In intensive farming mode, oxidative stress is caused by excessive production of reactive oxygen species in ruminants, which seriously threaten animal health and production performance by disrupting intestinal barrier integrity, damaging nutritional metabolism, and inducing inflammatory reactions. Research indicates that yeast supplementation can enhance ruminant health and production performance, while alleviating oxidative stress. Compared to traditional synthetic antioxidants, yeast and its cultures have emerged as preferred solutions due to their multi-target regulatory actions and inherent biosafety. This article focuses on ruminants and integrates recent research findings to systematically review the mechanisms underlying oxidative stress responses in animal organisms, the antioxidant defense system of animals, and the role of yeast and its cultures in enhancing animal antioxidant capacity, to provide ideas for analyzing effective strategies for regulating animal oxidative stress response.

摘要

在集约化养殖模式下,反刍动物体内活性氧的过度产生会引发氧化应激,这通过破坏肠道屏障完整性、损害营养代谢和引发炎症反应,严重威胁动物健康和生产性能。研究表明,补充酵母可以增强反刍动物的健康和生产性能,同时减轻氧化应激。与传统的合成抗氧化剂相比,酵母及其培养物因其多靶点调节作用和固有的生物安全性而成为首选解决方案。本文聚焦于反刍动物,整合近期研究结果,系统综述动物机体氧化应激反应的潜在机制、动物的抗氧化防御系统以及酵母及其培养物在增强动物抗氧化能力方面的作用,为分析调节动物氧化应激反应的有效策略提供思路。

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