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健康生活方式类别及得分趋势在高血压成年患者高血压管理中的作用。

The role of healthy lifestyle categories and score trend in managing hypertension among hypertensive adults.

作者信息

Vaezi Ali, Karimi Keyvan, Mirzad Mina, Khosravi Sepehr, Rezaei Nazila, Golestani Ali, Akbarpour Samaneh, Azadbakht Leila

机构信息

Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Sci Rep. 2025 Aug 25;15(1):31194. doi: 10.1038/s41598-025-16024-2.

Abstract

Despite the widespread use of antihypertensive medications, many patients struggle to achieve hypertension control, underscoring the need for additional strategies like lifestyle modification. Limited evidence exists on the impact of healthy lifestyle groups on hypertension control among individuals taking or not taking medication. This study assessed the effect of healthy lifestyle categories and scores on blood pressure control, systolic blood pressure (SBP), and diastolic blood pressure (DBP) among hypertensive adults in Iran. Data from the 2021 nationwide STEPwise Approach to non-communicable disease Risk Factor Surveillance survey were analyzed. Lifestyle variables, including physical activity, body mass index, alcohol consumption, tobacco use, and dietary habits, were scored for 9388 hypertensive adults ≥ 18 years across rural and urban regions from 2016 to 2021. Multivariable analysis, adjusted for antihypertensive medication use, showed that moderate and good lifestyle groups were associated with 9% (OR 0.91 [95% CI 0.85-1.04]) and 15% (OR 0.85 [95% CI 0.72-1.01]) lower odds of uncontrolled hypertension, respectively. These groups also significantly lowered SBP by - 1.22 (- 2.16 to - 0.23) and - 1.39 (- 2.54 to - 0.26) mmHg and DBP by - 1.01 (- 1.62 to - 0.41) and - 1.47 (- 2.21 to - 0.73) mmHg. These findings emphasize the potential of lifestyle interventions as part of public health strategies for blood pressure control.

摘要

尽管抗高血压药物被广泛使用,但许多患者仍难以实现高血压的控制,这凸显了采取如生活方式改变等额外策略的必要性。关于健康生活方式群组对正在服药或未服药个体的高血压控制的影响,现有证据有限。本研究评估了健康生活方式类别和得分对伊朗高血压成年人血压控制、收缩压(SBP)和舒张压(DBP)的影响。分析了2021年全国非传染性疾病风险因素监测逐步调查的数据。对2016年至2021年期间城乡地区9388名年龄≥18岁的高血压成年人的生活方式变量进行了评分,这些变量包括身体活动、体重指数、饮酒、吸烟和饮食习惯。经抗高血压药物使用调整后的多变量分析显示,中等和良好生活方式群组分别与未控制高血压几率降低9%(OR 0.91 [95% CI 0.85 - 1.04])和15%(OR 0.85 [95% CI 0.72 - 1.01])相关。这些群组还使收缩压分别显著降低 - 1.22(- 2.16至 - 0.23)和 - 1.39(- 2.54至 - 0.26)mmHg,舒张压分别显著降低 - 1.01(- 1.62至 - 0.41)和 - 1.47(- 2.21至 - 0.73)mmHg。这些发现强调了生活方式干预作为血压控制公共卫生策略一部分的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9468/12379248/3dd4c1ba2002/41598_2025_16024_Fig1_HTML.jpg

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