Lazarov Velik, Naseva Emilia, Miteva Dimitrina Georgieva, Tomov Latchezar P, Shumnalieva Russka, Peruhova Milena, Velikova Tsvetelina
Department of Obstetrics and Gynaecology, Second Specialised Hospital for Obstetrics and Gynaecology "Sheynovo", Sofia 1504, Bulgaria.
Faculty of Public Health, Medical University of Sofia, Sofia 1431, Bulgaria.
World J Transplant. 2025 Sep 18;15(3):103958. doi: 10.5500/wjt.v15.i3.103958.
Fertility preservation and pregnancymanagement are critical considerations for patients undergoing organtransplantation. Innovations in assisted reproductive technologies, hormonalmodulation, and personalized medicine have expanded options for these patients, who face unique challenges due to immunosuppressive therapy and organ functionconcerns. This mini-review explores advancements in cryopreservationtechniques, pre-conception counseling, and multidisciplinary strategies forsafe pregnancies post-transplantation. Emphasis is placed on balancing maternalhealth, graft function, and fetal outcomes. The integration of reproductive andtransplant medicine is paving the way for improved quality of life andreproductive autonomy for this patient population.
生育力保存和妊娠管理是器官移植患者的关键考虑因素。辅助生殖技术、激素调节和个性化医学的创新为这些患者扩展了选择,他们因免疫抑制治疗和器官功能问题面临独特挑战。本综述探讨了冷冻保存技术、孕前咨询以及移植后安全妊娠的多学科策略的进展。重点是平衡母体健康、移植物功能和胎儿结局。生殖医学与移植医学的整合正在为改善这一患者群体的生活质量和生殖自主权铺平道路。