Bassel J, Mortimer R
J Bacteriol. 1971 Oct;108(1):179-83. doi: 10.1128/jb.108.1.179-183.1971.
The galactose structural genes of Saccharomyces cerevisiae were ordered by determining the genotypes of mitotic and meiotic recombinants from crosses heterozygous for the three genes. The most probable order is centromere-gal7-gal10-gal1. Nonreciprocal recombination was more frequent than reciprocal exchange, and both mitotic and meiotic co-conversions involving mutant sites in all three genes were observed.
通过测定这三个基因杂合子杂交产生的有丝分裂和减数分裂重组体的基因型,对酿酒酵母的半乳糖结构基因进行了排序。最可能的顺序是着丝粒 - gal7 - gal10 - gal1。非相互重组比相互交换更频繁,并且观察到了涉及所有三个基因中突变位点的有丝分裂和减数分裂共转变。