[儿童糖尿病酮症酸中毒治疗并发急性脑水肿]
[Acute cerebral edema complicating therapy for diabetic ketoacidosis in children ].
作者信息
Jos J, Hubert P, Mselati J C, Chassevent J, Amédée-Manesme O
出版信息
Arch Fr Pediatr. 1982 Jun-Jul;39(6):375-7.
Cerebral edema complicating treatment of diabetic ketoacidosis does not seen to be very rare. This neurologic complication, which was observed in 3 cases, presents similarly in all patients, occurs mainly in children and adolescents and is usually lethal. Its mechanism has not been clearly explained yet. Various etiologic factors have been considered; sodium depletion, rapid infusion of hypotonic solutions and rapid fall of plasma glucose level might have a deleterious effect. On the basis of these data, some preventive therapeutic measures are proposed.
糖尿病酮症酸中毒治疗过程中并发的脑水肿似乎并不罕见。这种神经并发症在3例患者中被观察到，所有患者的表现相似，主要发生在儿童和青少年中，且通常是致命的。其机制尚未得到明确解释。已经考虑了各种病因因素；钠耗竭、低渗溶液的快速输注以及血浆葡萄糖水平的快速下降可能具有有害作用。基于这些数据，提出了一些预防性治疗措施。
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