库欣综合征：儿童尿道狭窄注射曲安奈德的并发症。

Cushing's syndrome: complication of triamcinolone injection for urethral strictures in children.

作者信息

Augspurger R R, Wettlaufer J N

出版信息

J Urol. 1980 Jun;123(6):932-3. doi: 10.1016/s0022-5347(17)56200-x.

PMID:7382013

Abstract

We report 2 cases of Cushing's syndrome following intralesional triamcinolone acetonide injections of urethral strictures in children. The pharmacology of triamcinolone and its 2 parenteral forms, triamcinolone acetonide and triamcinolone diacetate, is discussed. For children we recommend the short-acting triamcinolone diacetate at 4-week intervals with dosage adjusted to age. In adults either type of triamcinolone may be used but triamcinolone acetonide should be given at 6-week intervals.

摘要

我们报告了2例儿童尿道狭窄病灶内注射曲安奈德后发生库欣综合征的病例。本文讨论了曲安奈德及其两种肠胃外给药形式——曲安奈德醋酸酯和曲安奈德二醋酸酯的药理作用。对于儿童，我们建议使用短效的曲安奈德二醋酸酯，每隔4周注射一次，剂量根据年龄调整。对于成人，两种曲安奈德均可使用，但曲安奈德醋酸酯应每隔6周注射一次。