异基因造血干细胞移植后的移植物抗宿主效应：移植物抗宿主病和移植物抗白血病效应
Graft-versus-host effect after allogeneic hematopoietic stem cell transplantation: GVHD and GVL.
作者信息
Nash R A, Storb R
机构信息
Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.
出版信息
Curr Opin Immunol. 1996 Oct;8(5):674-80. doi: 10.1016/s0952-7915(96)80085-9.
PMID:8902393
Abstract
The development of a graft-versus-host reaction after allogeneic hematopoietic stem cell transplantation is an important determinant of the transplant outcome. A better understanding and improved management of the graft-versus-host reaction should allow improved prevention and treatment of graft-versus-host disease and the development of new strategies to enhance a graft-versus-leukemia effect and to decrease the incidence of leukemic relapse after transplantation.
摘要
异基因造血干细胞移植后移植物抗宿主反应的发生是移植结果的一个重要决定因素。更好地理解和改进移植物抗宿主反应的管理应有助于改善移植物抗宿主病的预防和治疗，并开发新的策略来增强移植物抗白血病效应，降低移植后白血病复发的发生率。
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