Maiuri F, Gangemi M, Iaconetta G, Signorelli F, Del Basso De Caro M
Department of Neurosurgery, School of Medicine, University Federico II, Naples, Italy.
Clin Neurol Neurosurg. 1997 Feb;99(1):17-22. doi: 10.1016/s0303-8467(96)00554-9.
Subependymomas are rare, slow-growing, benign intraventricular tumors, which often are asymptomatic and are discovered incidentally. The review of the literature shows more than 100 symptomatic cases, less than half located in the lateral ventricles. Here we report 8 cases of symptomatic subependymomas of the lateral ventricles, studied by CT and/or MR and treated by direct surgical approach. The suspicion of a subependymoma should arise when a patient older than 10-15 years with long clinical history presents an intraventricular tumor isodense on CT and isointense in T1 and hyperintense in T2 on MR, with scarce or discrete contrast enhancement. Surgical treatment is indicated in symptomatic subependymomas of the lateral ventricles and usually allows complete tumor removal. The prognosis is usually good, also without postoperative irradiation.
室管膜下瘤是一种罕见的、生长缓慢的良性脑室内肿瘤,通常无症状,多为偶然发现。文献回顾显示有100多例有症状的病例,其中不到一半位于侧脑室。本文报告8例有症状的侧脑室室管膜下瘤,均经CT和/或MR检查,并采用直接手术方法治疗。当10 - 15岁以上、有较长临床病史的患者出现脑室内肿瘤,CT表现为等密度、MR的T1加权像呈等信号、T2加权像呈高信号,且强化不明显或呈散在强化时,应怀疑为室管膜下瘤。有症状的侧脑室室管膜下瘤需行手术治疗,通常可完整切除肿瘤。其预后通常良好,术后也无需放疗。