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[热带念珠菌所致人工瓣膜心内膜炎的成功药物治疗]

[Successful medical treatment of Candida tropicalis in prosthetic valve endocarditis].

作者信息

Roel J E, Gamba A, Curone M, Pescio A, Bruno C, Finquelievich J

机构信息

Servicio de Internación, Clínica y Maternidad Suizo Argentina, Buenos Aires, Argentina.

出版信息

Medicina (B Aires). 1998;58(3):301-2.

PMID:9713102
Abstract

Medical cure of fungal prosthetic valve endocarditis (PVE) is rarely reported. We describe a patient with C. tropicalis PVE in whom surgery was believed to be contraindicated. A huge tricuspid valvular vegetation was identified by two-dimensional transthoracic echocardiography. After a total of 2 g of amphotericin B, she continued with fluconazole daily with a follow-up of fifteen months. Our patient represents the first case of long term survival of C. tropicalis PVE successfully managed without surgery.

摘要

真菌性人工瓣膜心内膜炎(PVE)的药物治愈鲜有报道。我们描述了一名热带念珠菌性PVE患者,该患者被认为不宜进行手术。经胸二维超声心动图检查发现巨大的三尖瓣赘生物。在总共使用2克两性霉素B后,她继续每日服用氟康唑,随访15个月。我们的患者代表了首例未经手术成功治疗的热带念珠菌性PVE长期存活病例。

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引用本文的文献

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Fungal Endocarditis.
Curr Infect Dis Rep. 2004 Aug;6(4):276-282. doi: 10.1007/s11908-004-0048-8.

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