Hux M J, O'Brien B J, Iskedjian M, Goeree R, Gagnon M, Gauthier S
Innovus Research Inc., Burlington, Ont.
CMAJ. 1998 Sep 8;159(5):457-65.
Data from the Canadian Study of Health and Aging (CSHA) were used to examine the relation between severity of Alzheimer's disease, as measured by the Mini-Mental State Examination (MMSE), and costs of caring.
The CSHA was a community-based survey of the prevalence of dementia, including subtypes such as Alzheimer's disease, among elderly Canadians. Survey subjects with a diagnosis of possible or probable Alzheimer's disease were grouped into disease severity levels of mild (MMSE score 21-26), mild to moderate (MMSE score 15-20), moderate (MMSE score 10-14) and severe (MMSE score below 10). Components of care available from the CSHA were use of nursing home care, use of medications, use of community support services by caregivers and unpaid caregiver time. Costs were calculated from a societal perspective and are expressed in 1996 Canadian dollars.
The annual societal cost of care per patient increased significantly with severity of Alzheimer's disease. The cost per patient was estimated to be $9451 for mild disease, $16,054 for mild to moderate disease, $25,724 for moderate disease and $36,794 for severe disease. Institutionalization was the largest component of cost, accounting for as much as 84% of the cost for people with severe disease. For subjects living in the community, unpaid caregiver time and use of community services were the greatest components of cost and increased with disease severity.
The societal cost of care of Alzheimer's disease increases drastically with increasing disease severity. Institutionalization is responsible for the largest cost component.
加拿大健康与老龄化研究(CSHA)的数据被用于研究以简易精神状态检查表(MMSE)衡量的阿尔茨海默病严重程度与护理成本之间的关系。
CSHA是一项针对加拿大老年人痴呆症患病率的社区调查,包括阿尔茨海默病等亚型。被诊断为可能或很可能患有阿尔茨海默病的调查对象被分为轻度(MMSE评分21 - 26)、轻度至中度(MMSE评分15 - 20)、中度(MMSE评分10 - 14)和重度(MMSE评分低于10)疾病严重程度级别。CSHA中可获得的护理组成部分包括使用养老院护理、使用药物、护理人员使用社区支持服务以及无薪护理人员的时间。成本从社会角度计算,并以1996年加拿大元表示。
每位患者的年度社会护理成本随着阿尔茨海默病严重程度的增加而显著增加。轻度疾病患者的人均成本估计为9451加元,轻度至中度疾病患者为16,054加元,中度疾病患者为25,724加元,重度疾病患者为36,794加元。机构化护理是成本的最大组成部分,占重度疾病患者成本的84%。对于居住在社区的患者,无薪护理人员的时间和社区服务的使用是成本的最大组成部分,并随着疾病严重程度的增加而增加。
阿尔茨海默病的社会护理成本随着疾病严重程度的增加而急剧上升。机构化护理是最大的成本组成部分。