肺炎链球菌的致病因素及所致疾病的发病机制。
Virulence factors and the pathogenesis of disease caused by Streptococcus pneumoniae.
作者信息
Mitchell T J
机构信息
Division of Infection and Immunity, Institute of Biomedical and Life Sciences, University of Glasgow, Scotland, UK.
出版信息
Res Microbiol. 2000 Jul-Aug;151(6):413-9. doi: 10.1016/s0923-2508(00)00175-3.
Abstract
Streptococcus pneumoniae is a major pathogen of man causing diseases such as pneumonia, meningitis and otitis media. The mechanisms by which this organism causes these diseases are still largely unknown. The use of molecular approaches to identifying and studying putative virulence factors in combination with the application of animal models has allowed some of the mechanisms of the disease process to be defined.
摘要
肺炎链球菌是人类的主要病原体，可引发诸如肺炎、脑膜炎和中耳炎等疾病。该生物体引发这些疾病的机制在很大程度上仍不为人知。运用分子方法来识别和研究假定的毒力因子，并结合动物模型的应用，已经使疾病过程的一些机制得以明确。
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