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胰腺癌与糖尿病

Pancreatic cancer and sugar diabetes.

作者信息

DeMeo M T

机构信息

Division of Digestive Diseases and Nutrition, Rush University Medical Center, Chicago, IL 60612, USA.

出版信息

Nutr Rev. 2001 Apr;59(4):112-5. doi: 10.1111/j.1753-4887.2001.tb06997.x.

Abstract

The link between pancreatic cancer and diabetes mellitus is well recognized. Controversy still exists, however, as to whether the pancreatic cancer is the cause of abnormal glucose metabolism or if hyperinsulinemia predisposes the person to pancreatic cancer. A recent article offers strong data supporting diabetes as a risk factor for pancreatic cancer. Patients with abnormal glucose metabolism, as determined by elevated serum glucose 1 hour after an oral glucose challenge, were found to have an increased risk of developing pancreatic carcinoma even if patients dying from that disease during the first 5 years of follow-up were excluded from consideration.

摘要

胰腺癌与糖尿病之间的联系已得到广泛认可。然而,关于胰腺癌是异常糖代谢的原因,还是高胰岛素血症使个体易患胰腺癌,仍存在争议。最近一篇文章提供了有力数据支持糖尿病是胰腺癌的一个风险因素。通过口服葡萄糖耐量试验后1小时血清葡萄糖升高来确定糖代谢异常的患者,即使排除随访前5年内死于该疾病的患者,仍发现其患胰腺癌的风险增加。

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