人们正在寻找电压传感器与门之间的耦合。 - Suppr

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超能文献

The search is on for the voltage sensor-to-gate coupling.

作者信息

Larsson H Peter

机构信息

Neurological Sciences Institute, Oregon Health and Science University, Beaverton, OR 97006, USA.

出版信息

J Gen Physiol. 2002 Oct;120(4):475-81. doi: 10.1085/jgp.20028657.

DOI:10.1085/jgp.20028657

PMID:12356850

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2229528/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f86/2229528/fe456ca529bc/20028657f1.jpg

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引用本文的文献

Loose Coupling between the Voltage Sensor and the Activation Gate in Mammalian HCN Channels Suggests a Gating Mechanism.

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A quantitative description of membrane current and its application to conduction and excitation in nerve.

J Physiol. 1952 Aug;117(4):500-44. doi: 10.1113/jphysiol.1952.sp004764.

Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.

Nature. 2002 Oct 24;419(6909):837-41. doi: 10.1038/nature01038.

Voltage sensor movements.

J Gen Physiol. 2002 Oct;120(4):465-73. doi: 10.1085/jgp.20028660.

Molecular models of voltage sensing.

J Gen Physiol. 2002 Oct;120(4):455-63. doi: 10.1085/jgp.20028678.

The open pore conformation of potassium channels.

Nature. 2002 May 30;417(6888):523-6. doi: 10.1038/417523a.

Crystal structure and mechanism of a calcium-gated potassium channel.

Nature. 2002 May 30;417(6888):515-22. doi: 10.1038/417515a.

Fast and slow voltage sensor movements in HERG potassium channels.

J Gen Physiol. 2002 Mar;119(3):275-93. doi: 10.1085/jgp.20028534.

Voltage-controlled gating at the intracellular entrance to a hyperpolarization-activated cation channel.

J Gen Physiol. 2002 Jan;119(1):83-91. doi: 10.1085/jgp.119.1.83.

Tight steric closure at the intracellular activation gate of a voltage-gated K(+) channel.

Neuron. 2001 Nov 20;32(4):649-56. doi: 10.1016/s0896-6273(01)00487-1.

Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution.

Nature. 2001 Nov 1;414(6859):43-8. doi: 10.1038/35102009.

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相似文献

The search is on for the voltage sensor-to-gate coupling.

J Gen Physiol. 2002 Oct;120(4):475-81. doi: 10.1085/jgp.20028657.

Voltage sensor movements.

J Gen Physiol. 2002 Oct;120(4):465-73. doi: 10.1085/jgp.20028660.

Changes in local S4 environment provide a voltage-sensing mechanism for mammalian hyperpolarization-activated HCN channels.

J Gen Physiol. 2004 Jan;123(1):5-19. doi: 10.1085/jgp.200308918. Epub 2003 Dec 15.

Gating motions in voltage-gated potassium channels revealed by coarse-grained molecular dynamics simulations.

J Phys Chem B. 2008 Mar 20;112(11):3277-82. doi: 10.1021/jp709675e. Epub 2008 Feb 23.

[The surface charge theory and influences of sialic acid on the gating of sodium and potassium channels].

Sheng Li Ke Xue Jin Zhan. 2004 Apr;35(2):167-9.

KCNE1 and KCNE3 modulate KCNQ1 channels by affecting different gating transitions.

Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):E7367-E7376. doi: 10.1073/pnas.1710335114. Epub 2017 Aug 14.

Voltage-gated ion channels.

Curr Biol. 2005 Jan 26;15(2):R44-7. doi: 10.1016/j.cub.2004.12.050.

Molecular models of voltage sensing.

J Gen Physiol. 2002 Oct;120(4):455-63. doi: 10.1085/jgp.20028678.

Gating mechanism of BK (Slo1) channels: so near, yet so far.

J Gen Physiol. 2003 Feb;121(2):81-96. doi: 10.1085/jgp.20028721.

Coupled movements in voltage-gated ion channels.

J Gen Physiol. 2002 Oct;120(4):449-53. doi: 10.1085/jgp.20028658.

引用本文的文献

Loose Coupling between the Voltage Sensor and the Activation Gate in Mammalian HCN Channels Suggests a Gating Mechanism.

Int J Mol Sci. 2024 Apr 13;25(8):4309. doi: 10.3390/ijms25084309.

Gating interaction maps reveal a noncanonical electromechanical coupling mode in the Shaker K channel.

Nat Struct Mol Biol. 2018 Apr;25(4):320-326. doi: 10.1038/s41594-018-0047-3. Epub 2018 Mar 26.

Characterization of the PCMBS-dependent modification of KCa3.1 channel gating.

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Intramembrane charge movement associated with endogenous K+ channel activity in HEK-293 cells.

Cell Mol Neurobiol. 2004 Jun;24(3):317-30. doi: 10.1023/b:cemn.0000022765.52109.26.

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J Gen Physiol. 2004 Mar;123(3):205-16. doi: 10.1085/jgp.200308993. Epub 2004 Feb 9.

Changes in local S4 environment provide a voltage-sensing mechanism for mammalian hyperpolarization-activated HCN channels.

J Gen Physiol. 2004 Jan;123(1):5-19. doi: 10.1085/jgp.200308918. Epub 2003 Dec 15.

S4 movement in a mammalian HCN channel.

J Gen Physiol. 2004 Jan;123(1):21-32. doi: 10.1085/jgp.200308916. Epub 2003 Dec 15.

Coupled movements in voltage-gated ion channels.

J Gen Physiol. 2002 Oct;120(4):449-53. doi: 10.1085/jgp.20028658.

本文引用的文献

A quantitative description of membrane current and its application to conduction and excitation in nerve.

J Physiol. 1952 Aug;117(4):500-44. doi: 10.1113/jphysiol.1952.sp004764.

Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.

Nature. 2002 Oct 24;419(6909):837-41. doi: 10.1038/nature01038.

Voltage sensor movements.

J Gen Physiol. 2002 Oct;120(4):465-73. doi: 10.1085/jgp.20028660.

Molecular models of voltage sensing.

J Gen Physiol. 2002 Oct;120(4):455-63. doi: 10.1085/jgp.20028678.

The open pore conformation of potassium channels.

Nature. 2002 May 30;417(6888):523-6. doi: 10.1038/417523a.

Crystal structure and mechanism of a calcium-gated potassium channel.

Nature. 2002 May 30;417(6888):515-22. doi: 10.1038/417515a.

Fast and slow voltage sensor movements in HERG potassium channels.

J Gen Physiol. 2002 Mar;119(3):275-93. doi: 10.1085/jgp.20028534.

Voltage-controlled gating at the intracellular entrance to a hyperpolarization-activated cation channel.

J Gen Physiol. 2002 Jan;119(1):83-91. doi: 10.1085/jgp.119.1.83.

Tight steric closure at the intracellular activation gate of a voltage-gated K(+) channel.

Neuron. 2001 Nov 20;32(4):649-56. doi: 10.1016/s0896-6273(01)00487-1.

Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution.

Nature. 2001 Nov 1;414(6859):43-8. doi: 10.1038/35102009.