Heuss L T, Froehlich F, Beglinger C
Department of Gastroenterology, University Hospital, Basle, Switzerland.
Endoscopy. 2005 Feb;37(2):161-6. doi: 10.1055/s-2004-826143.
Little is known about how practices in sedation and in monitoring during gastrointestinal endoscopy and the complication rates of sedation have changed over time. The aim of this nationwide survey was to assess the present practice among Swiss gastroenterologists, with a particular focus on the use of propofol, and to compare the results with similar data obtained in 1990.
At the end of 2003 a questionnaire (similar to the one used in 1990) was sent to all 249 Swiss gastroenterologists. The response rate was 72.3 %. Data from 179 953 endoscopies performed during the previous 12 months were analyzed for the study.
In 2003 sedation was used in 78 % of esophagogastroduodenoscopies and colonoscopies (compared with 60 % in 1990), with midazolam being the most commonly used medication. The drugs were mostly administered by the endoscopy nurse, via an intravenous cannula. Oximetry monitoring was used in more than 95 % of examinations (compared with 2.5 % in 1990). The overall sedation-related morbidity was 0.18 % and the mortality rate was 0.0014 %. Of the 180 respondents, 77 (43 %) reported that they been using propofol regularly for a median time period of 23 months. The 62 respondents (34 %) who used propofol without the assistance of an anesthesiologist had performed a total of 82 620 procedures. The morbidity (defined as the need for bag-ventilation) in this group of patients was 0.19 % and no deaths were reported.
The use of sedation in gastrointestinal endoscopy has markedly increased over the last 13 years and the use of electronic monitoring has become standard practice. A significant percentage of Swiss gastroenterologists report that they use propofol, mainly in a hospital setting.
关于胃肠内镜检查期间的镇静操作及监测方法,以及镇静并发症发生率随时间的变化情况,目前所知甚少。这项全国性调查的目的是评估瑞士胃肠病学家目前的操作情况,尤其关注丙泊酚的使用,并将结果与1990年获得的类似数据进行比较。
2003年底,向所有249名瑞士胃肠病学家发送了一份问卷(与1990年使用的问卷类似)。回复率为72.3%。对前12个月内进行的179953例内镜检查的数据进行了分析研究。
2003年,78%的食管胃十二指肠镜检查和结肠镜检查使用了镇静(1990年为60%),咪达唑仑是最常用的药物。这些药物大多由内镜护士通过静脉套管给药。超过95%的检查使用了血氧饱和度监测(1990年为2.5%)。镇静相关的总体发病率为0.18%,死亡率为0.0014%。在180名受访者中,77人(43%)报告称他们定期使用丙泊酚,中位使用时间为2个月。62名(34%)在没有麻醉医生协助的情况下使用丙泊酚的受访者共进行了82620例操作。该组患者的发病率(定义为需要进行球囊通气)为0.19%,未报告死亡病例。
在过去13年中,胃肠内镜检查中镇静的使用显著增加,电子监测已成为标准操作。相当比例的瑞士胃肠病学家报告称他们使用丙泊酚,主要是在医院环境中。