Daousi C, Casson I F, Gill G V, MacFarlane I A, Wilding J P H, Pinkney J H
Diabetes and Endocrinology Research Group, University Hospital Aintree, Liverpool, UK.
Postgrad Med J. 2006 Apr;82(966):280-4. doi: 10.1136/pmj.2005.039032.
To determine the prevalence of overweight and obesity among patients with type 1 and type 2 diabetes mellitus attending a secondary care diabetes clinic in the United Kingdom, and to assess the impact of overweight and obesity on glycaemic control and cardiovascular risk factors in patients with type 2 diabetes.
3637 patients with diabetes were identified from the hospital electronic diabetes register, 916 with type 1 diabetes (mean (SD) age 40.4 (15.1) years, 496 male) and 2721 with type 2 diabetes (mean (SD) age 62.5 (11.8) years, 1436 male). Data on body mass index (BMI), glycaemic control, lipid profiles, and blood pressure were extracted.
Of patients with type 1 diabetes, 55.3% were overweight (BMI >or=25 kg/m(2)), 16.6% were obese (BMI >or=30 kg/m(2)), and 0.4% had morbid obesity (BMI >or=40 kg/m(2)). In contrast, 86% of patients with type 2 diabetes were overweight or obese, 52% were obese, and 8.1% had morbid obesity. Obese patients with type 2 diabetes were younger, had poorer glycaemic control, higher blood pressures, worse lipid profiles, and were more likely to be receiving antihypertensive and lipid lowering drugs compared with patients with BMI <30 kg/m(2).
Obesity is the rule among patients attending this hospital diabetes clinic, with 86% of those with type 2 diabetes overweight or obese. Obesity is associated with significantly worse cardiovascular risk factors in this patient group, suggesting that more active interventions to control weight gain would be appropriate.
确定在英国一家二级护理糖尿病诊所就诊的1型和2型糖尿病患者中超重和肥胖的患病率,并评估超重和肥胖对2型糖尿病患者血糖控制和心血管危险因素的影响。
从医院电子糖尿病登记册中识别出3637例糖尿病患者,其中916例为1型糖尿病患者(平均(标准差)年龄40.4(15.1)岁,男性496例),2721例为2型糖尿病患者(平均(标准差)年龄62.5(11.8)岁,男性1436例)。提取了体重指数(BMI)、血糖控制、血脂谱和血压的数据。
1型糖尿病患者中,55.3%超重(BMI≥25kg/m²),16.6%肥胖(BMI≥30kg/m²),0.4%患有病态肥胖(BMI≥40kg/m²)。相比之下,86%的2型糖尿病患者超重或肥胖,52%肥胖,8.1%患有病态肥胖。与BMI<30kg/m²的患者相比,2型糖尿病肥胖患者更年轻,血糖控制更差,血压更高,血脂谱更差,且更有可能正在接受抗高血压和降脂药物治疗。
在这家医院糖尿病诊所就诊的患者中,肥胖是常态,86%的2型糖尿病患者超重或肥胖。在该患者群体中,肥胖与明显更差的心血管危险因素相关,这表明采取更积极的干预措施来控制体重增加是合适的。