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二级医疗中2型糖尿病患者的肥胖患病率:与心血管危险因素的关联

Prevalence of obesity in type 2 diabetes in secondary care: association with cardiovascular risk factors.

作者信息

Daousi C, Casson I F, Gill G V, MacFarlane I A, Wilding J P H, Pinkney J H

机构信息

Diabetes and Endocrinology Research Group, University Hospital Aintree, Liverpool, UK.

出版信息

Postgrad Med J. 2006 Apr;82(966):280-4. doi: 10.1136/pmj.2005.039032.

Abstract

AIMS

To determine the prevalence of overweight and obesity among patients with type 1 and type 2 diabetes mellitus attending a secondary care diabetes clinic in the United Kingdom, and to assess the impact of overweight and obesity on glycaemic control and cardiovascular risk factors in patients with type 2 diabetes.

METHODS

3637 patients with diabetes were identified from the hospital electronic diabetes register, 916 with type 1 diabetes (mean (SD) age 40.4 (15.1) years, 496 male) and 2721 with type 2 diabetes (mean (SD) age 62.5 (11.8) years, 1436 male). Data on body mass index (BMI), glycaemic control, lipid profiles, and blood pressure were extracted.

RESULTS

Of patients with type 1 diabetes, 55.3% were overweight (BMI >or=25 kg/m(2)), 16.6% were obese (BMI >or=30 kg/m(2)), and 0.4% had morbid obesity (BMI >or=40 kg/m(2)). In contrast, 86% of patients with type 2 diabetes were overweight or obese, 52% were obese, and 8.1% had morbid obesity. Obese patients with type 2 diabetes were younger, had poorer glycaemic control, higher blood pressures, worse lipid profiles, and were more likely to be receiving antihypertensive and lipid lowering drugs compared with patients with BMI <30 kg/m(2).

CONCLUSIONS

Obesity is the rule among patients attending this hospital diabetes clinic, with 86% of those with type 2 diabetes overweight or obese. Obesity is associated with significantly worse cardiovascular risk factors in this patient group, suggesting that more active interventions to control weight gain would be appropriate.

摘要

目的

确定在英国一家二级护理糖尿病诊所就诊的1型和2型糖尿病患者中超重和肥胖的患病率,并评估超重和肥胖对2型糖尿病患者血糖控制和心血管危险因素的影响。

方法

从医院电子糖尿病登记册中识别出3637例糖尿病患者,其中916例为1型糖尿病患者(平均(标准差)年龄40.4(15.1)岁,男性496例),2721例为2型糖尿病患者(平均(标准差)年龄62.5(11.8)岁,男性1436例)。提取了体重指数(BMI)、血糖控制、血脂谱和血压的数据。

结果

1型糖尿病患者中,55.3%超重(BMI≥25kg/m²),16.6%肥胖(BMI≥30kg/m²),0.4%患有病态肥胖(BMI≥40kg/m²)。相比之下,86%的2型糖尿病患者超重或肥胖,52%肥胖,8.1%患有病态肥胖。与BMI<30kg/m²的患者相比,2型糖尿病肥胖患者更年轻,血糖控制更差,血压更高,血脂谱更差,且更有可能正在接受抗高血压和降脂药物治疗。

结论

在这家医院糖尿病诊所就诊的患者中,肥胖是常态,86%的2型糖尿病患者超重或肥胖。在该患者群体中,肥胖与明显更差的心血管危险因素相关,这表明采取更积极的干预措施来控制体重增加是合适的。

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