对来自爵床的七种芳基萘内酯木脂素的¹H和¹³C NMR数据进行完整归属。

Complete assignments of 1H and 13C NMR data for seven arylnaphthalide lignans from Justicia procumbens.

作者信息

Yang Meihua, Wu Jun, Cheng Fan, Zhou Yuan

机构信息

Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100094, P.R. China.

出版信息

Magn Reson Chem. 2006 Jul;44(7):727-30. doi: 10.1002/mrc.1830.

DOI:10.1002/mrc.1830

PMID:16625672

Abstract

Three new arylnaphthalide lignans named 6'-hydroxy justicidin A (1), 6'-hydroxy justicidin B (2) and 6'-hydroxy justicidin C (3) have been isolated from the whole plant of Justicia procumbens, together with four known ones, neojusticin A (4), chinensinaphthol methyl ester (5), isodiphyllin (6) and taiwanin C (7). The complete assignments of 1H and 13C NMR chemical shifts for the new lignans and the 13C NMR chemical shifts for the known lignans were obtained for the first time by means of 2D NMR techniques, including HSQC and HMBC.

摘要

从匍匐爵床全草中分离得到了三种新的芳基萘内酯木脂素，分别命名为6'-羟基异爵床脂素A（1）、6'-羟基异爵床脂素B（2）和6'-羟基异爵床脂素C（3），同时还得到了四种已知的木脂素，新异爵床脂素A（4）、中华萘酚甲酯（5）、异二叶豆素（6）和台湾脂素C（7）。通过二维核磁共振技术（包括HSQC和HMBC）首次获得了新木脂素的¹H和¹³C NMR化学位移以及已知木脂素的¹³C NMR化学位移的完整归属。