纳米技术在医学中的应用。

Nanotechnological applications in medicine.

作者信息

Caruthers Shelton D, Wickline Samuel A, Lanza Gregory M

机构信息

Consortium for Translational Research in Advanced Imaging and Nanomedicine, Washington University School of Medicine, 4444 Forest Park Avenue, Campus Box 8215, St Louis, MO 63108-2212, USA.

出版信息

Curr Opin Biotechnol. 2007 Feb;18(1):26-30. doi: 10.1016/j.copbio.2007.01.006. Epub 2007 Jan 24.

DOI:10.1016/j.copbio.2007.01.006

PMID:17254762

Abstract

Nanotechnology-based tools and techniques are rapidly emerging in the fields of medical imaging and targeted drug delivery. Employing constructs such as dendrimers, liposomes, nanoshells, nanotubes, emulsions and quantum dots, these advances lead toward the concept of personalized medicine and the potential for very early, even pre-symptomatic, diagnoses coupled with highly-effective targeted therapy. Highlighting clinically available and preclinical applications, this review explores the opportunities and issues surrounding nanomedicine.

摘要

基于纳米技术的工具和技术正在医学成像和靶向药物递送领域迅速兴起。利用诸如树枝状大分子、脂质体、纳米壳、纳米管、乳剂和量子点等构建体，这些进展朝着个性化医疗的概念以及实现非常早期甚至症状前诊断并结合高效靶向治疗的可能性迈进。本综述突出了临床可用和临床前应用，探讨了纳米医学周围的机遇和问题。